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A Poly-ADP-Ribose Polymer-GCSF Conjugate.
Cheng Q, Zhang XN, Zhang L, Chen J, Wang Y, Zhang Y. Cheng Q, et al. Biomacromolecules. 2022 Dec 12;23(12):5267-5272. doi: 10.1021/acs.biomac.2c01090. Epub 2022 Nov 9. Biomacromolecules. 2022. PMID: 36350184 Free PMC article.
Discovery of an NAD+ analogue with enhanced specificity for PARP1.
Zhang XN, Lam AT, Cheng Q, Courouble VV, Strutzenberg TS, Li J, Wang Y, Pei H, Stiles BL, Louie SG, Griffin PR, Zhang Y. Zhang XN, et al. Chem Sci. 2022 Jan 27;13(7):1982-1991. doi: 10.1039/d1sc06256e. eCollection 2022 Feb 16. Chem Sci. 2022. PMID: 35308855 Free PMC article.
EFEMP1 rare variants cause familial juvenile-onset open-angle glaucoma.
Collantes ERA, Delfin MS, Fan B, Torregosa JMR, Siguan-Bell C, Florcruz NVG, Martinez JMD, Masna-Hidalgo BJ, Guzman VPT, Anotado-Flores JF, Levina FD, Hernandez SRC, Collantes AA, Sibulo MC, Rong S, Wiggs JL. Collantes ERA, et al. Hum Mutat. 2022 Feb;43(2):240-252. doi: 10.1002/humu.24320. Epub 2021 Dec 28. Hum Mutat. 2022. PMID: 34923728 Free PMC article.