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The neuronal nitric oxide synthase inhibitor NANT blocks acetaminophen toxicity and protein nitration in freshly isolated hepatocytes.
Free Radic Biol Med. 2015 Dec;89:750-7. doi: 10.1016/j.freeradbiomed.2015.09.022. Epub 2015 Oct 9.
Free Radic Biol Med. 2015.
PMID: 26454079
Free PMC article.
Potential of extracellular microRNAs as biomarkers of acetaminophen toxicity in children.
Yang X, Salminen WF, Shi Q, Greenhaw J, Gill PS, Bhattacharyya S, Beger RD, Mendrick DL, Mattes WB, James LP.
Yang X, et al.
Toxicol Appl Pharmacol. 2015 Apr 15;284(2):180-7. doi: 10.1016/j.taap.2015.02.013. Epub 2015 Feb 21.
Toxicol Appl Pharmacol. 2015.
PMID: 25708609
Free PMC article.
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Targeted liquid chromatography-mass spectrometry analysis of serum acylcarnitines in acetaminophen toxicity in children.
Bhattacharyya S, Yan K, Pence L, Simpson PM, Gill P, Letzig LG, Beger RD, Sullivan JE, Kearns GL, Reed MD, Marshall JD, Van Den Anker JN, James LP.
Bhattacharyya S, et al.
Biomark Med. 2014;8(2):147-59. doi: 10.2217/bmm.13.150.
Biomark Med. 2014.
PMID: 24521011
Free PMC article.
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Acetaminophen-induced hepatotoxicity and protein nitration in neuronal nitric-oxide synthase knockout mice.
Agarwal R, Hennings L, Rafferty TM, Letzig LG, McCullough S, James LP, MacMillan-Crow LA, Hinson JA.
Agarwal R, et al.
J Pharmacol Exp Ther. 2012 Jan;340(1):134-42. doi: 10.1124/jpet.111.184192. Epub 2011 Oct 14.
J Pharmacol Exp Ther. 2012.
PMID: 22001257
Free PMC article.
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Acetaminophen-induced hepatotoxicity in mice occurs with inhibition of activity and nitration of mitochondrial manganese superoxide dismutase.
Agarwal R, MacMillan-Crow LA, Rafferty TM, Saba H, Roberts DW, Fifer EK, James LP, Hinson JA.
Agarwal R, et al.
J Pharmacol Exp Ther. 2011 Apr;337(1):110-6. doi: 10.1124/jpet.110.176321. Epub 2010 Dec 30.
J Pharmacol Exp Ther. 2011.
PMID: 21205919
Free PMC article.
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