R01 DK133479/DK/NIDDK NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2022	2
2023	6
2024	4

1

Membrane-bound O-acyltransferase 7 (MBOAT7) shapes lysosomal lipid homeostasis and function to control alcohol-associated liver injury.

Varadharajan V, Ramachandiran I, Massey WJ, Jain R, Banerjee R, Horak AJ, McMullen MR, Huang E, Bellar A, Lorkowski SW, Gulshan K, Helsley RN, James I, Pathak V, Dasarathy J, Welch N, Dasarathy S, Streem D, Reizes O, Allende DS, Smith JD, Simcox J, Nagy LE, Brown JM. Varadharajan V, et al. Elife. 2024 Apr 22;12:RP92243. doi: 10.7554/eLife.92243. Elife. 2024. PMID: 38648183 Free PMC article.

2

Dietary lipid is largely deposited in skin and rapidly affects insulating properties.

Riley N, Kasza I, Barrett-Wilt G, Michaud J, Jain R, Trautman ME, Simcox JA, Yen CE, MacDougald OA, Lamming DW, Alexander CM. Riley N, et al. Res Sq [Preprint]. 2024 Feb 22:rs.3.rs-3957002. doi: 10.21203/rs.3.rs-3957002/v1. Res Sq. 2024. PMID: 38464106 Free PMC article. Preprint.

3

Dietary restriction of isoleucine increases healthspan and lifespan of genetically heterogeneous mice.

Green CL, Trautman ME, Chaiyakul K, Jain R, Alam YH, Babygirija R, Pak HH, Sonsalla MM, Calubag MF, Yeh CY, Bleicher A, Novak G, Liu TT, Newman S, Ricke WA, Matkowskyj KA, Ong IM, Jang C, Simcox J, Lamming DW. Green CL, et al. Cell Metab. 2023 Nov 7;35(11):1976-1995.e6. doi: 10.1016/j.cmet.2023.10.005. Cell Metab. 2023. PMID: 37939658

4

Blazing a trail for the clinical use of rapamycin as a geroprotecTOR.

Konopka AR, Lamming DW; RAP PAC Investigators; EVERLAST Investigators. Konopka AR, et al. Geroscience. 2023 Oct;45(5):2769-2783. doi: 10.1007/s11357-023-00935-x. Epub 2023 Oct 6. Geroscience. 2023. PMID: 37801202 Free PMC article.

5

Protein restriction slows the development and progression of Alzheimer's disease in mice.

Babygirija R, Sonsalla MM, Mill J, James I, Han JH, Green CL, Calubag MF, Wade G, Tobon A, Michael J, Trautman MM, Matoska R, Yeh CY, Grunow I, Pak HH, Rigby MJ, Baldwin DA, Niemi NM, Denu JM, Puglielli L, Simcox J, Lamming DW. Babygirija R, et al. Res Sq [Preprint]. 2024 Apr 24:rs.3.rs-3342413. doi: 10.21203/rs.3.rs-3342413/v1. Res Sq. 2024. PMID: 37790423 Free PMC article. Preprint.

6

Ormdl3 regulation of specific ceramides is dispensable for mouse β-cell function and glucose homeostasis under obesogenic conditions.

Hurley LD, Lee H, Wade G, Simcox J, Engin F. Hurley LD, et al. Front Endocrinol (Lausanne). 2023 Apr 14;14:1170461. doi: 10.3389/fendo.2023.1170461. eCollection 2023. Front Endocrinol (Lausanne). 2023. PMID: 37124760 Free PMC article.

7

Ormdl3 regulation of specific ceramides is dispensable for β-cell function and glucose homeostasis under obesogenic conditions.

Hurley LD, Lee H, Wade G, Simcox J, Engin F. Hurley LD, et al. bioRxiv [Preprint]. 2023 Feb 11:2023.02.11.528130. doi: 10.1101/2023.02.11.528130. bioRxiv. 2023. PMID: 36798417 Free PMC article. Updated. Preprint.

8

Late-life isoleucine restriction promotes physiological and molecular signatures of healthy aging.

Yeh CY, Chini LCS, Davidson JW, Garcia GG, Gallagher MS, Freichels IT, Calubag MF, Rodgers AC, Green CL, Babygirija R, Sonsalla MM, Pak HH, Trautman M, Hacker TA, Miller RA, Simcox J, Lamming DW. Yeh CY, et al. bioRxiv [Preprint]. 2024 Jan 9:2023.02.06.527311. doi: 10.1101/2023.02.06.527311. bioRxiv. 2024. PMID: 36798157 Free PMC article. Preprint.

9

SON-light activation of glucose regulation.

Geoghegan G, Simcox J. Geoghegan G, et al. Cell. 2023 Jan 19;186(2):238-240. doi: 10.1016/j.cell.2022.12.045. Cell. 2023. PMID: 36669471 Free PMC article.

10

Hepatic Oleate Regulates Insulin-like Growth Factor-Binding Protein 1 Partially through the mTORC1-FGF21 Axis during High-Carbohydrate Feeding.

O'Neill LM, Phang YX, Liu Z, Lewis SA, Aljohani A, McGahee A, Wade G, Kalyesubula M, Simcox J, Ntambi JM. O'Neill LM, et al. Int J Mol Sci. 2022 Nov 24;23(23):14671. doi: 10.3390/ijms232314671. Int J Mol Sci. 2022. PMID: 36498997 Free PMC article.

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