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A human iPSC-array-based GWAS identifies a virus susceptibility locus in the NDUFA4 gene and functional variants.
Han Y, Tan L, Zhou T, Yang L, Carrau L, Lacko LA, Saeed M, Zhu J, Zhao Z, Nilsson-Payant BE, Lira Neto FT, Cahir C, Giani AM, Chai JC, Li Y, Dong X, Moroziewicz D; NYSCF Global Stem Cell Array Team; Paull D, Zhang T, Koo S, Tan C, Danziger R, Ba Q, Feng L, Chen Z, Zhong A, Wise GJ, Xiang JZ, Wang H, Schwartz RE, tenOever BR, Noggle SA, Rice CM, Qi Q, Evans T, Chen S. Han Y, et al. Cell Stem Cell. 2022 Oct 6;29(10):1475-1490.e6. doi: 10.1016/j.stem.2022.09.008. Cell Stem Cell. 2022. PMID: 36206731 Free PMC article.
A dual SHOX2:GFP; MYH6:mCherry knockin hESC reporter line for derivation of human SAN-like cells.
Ghazizadeh Z, Zhu J, Fattahi F, Tang A, Sun X, Amin S, Tsai SY, Khalaj M, Zhou T, Samuel RM, Zhang T, Ortega FA, Gordillo M, Moroziewicz D; NYSCF Global Stem Cell Array® Team; Paull D, Noggle SA, Xiang JZ, Studer L, Christini DJ, Pitt GS, Evans T, Chen S. Ghazizadeh Z, et al. iScience. 2022 Mar 25;25(4):104153. doi: 10.1016/j.isci.2022.104153. eCollection 2022 Apr 15. iScience. 2022. PMID: 35434558 Free PMC article.
SARS-CoV-2 Infection Induces Ferroptosis of Sinoatrial Node Pacemaker Cells.
Han Y, Zhu J, Yang L, Nilsson-Payant BE, Hurtado R, Lacko LA, Sun X, Gade AR, Higgins CA, Sisso WJ, Dong X, Wang M, Chen Z, Ho DD, Pitt GS, Schwartz RE, tenOever BR, Evans T, Chen S. Han Y, et al. Circ Res. 2022 Apr;130(7):963-977. doi: 10.1161/CIRCRESAHA.121.320518. Epub 2022 Mar 8. Circ Res. 2022. PMID: 35255712 Free PMC article.
Mechanisms of Lung Injury Induced by SARS-CoV-2 Infection.
Upadhya S, Rehman J, Malik AB, Chen S. Upadhya S, et al. Physiology (Bethesda). 2022 Mar 1;37(2):88-100. doi: 10.1152/physiol.00033.2021. Epub 2021 Oct 26. Physiology (Bethesda). 2022. PMID: 34698589 Free PMC article. Review.
Cardiomyocytes recruit monocytes upon SARS-CoV-2 infection by secreting CCL2.
Yang L, Nilsson-Payant BE, Han Y, Jaffré F, Zhu J, Wang P, Zhang T, Redmond D, Houghton S, Møller R, Hoagland D, Carrau L, Horiuchi S, Goff M, Lim JK, Bram Y, Richardson C, Chandar V, Borczuk A, Huang Y, Xiang J, Ho DD, Schwartz RE, tenOever BR, Evans T, Chen S. Yang L, et al. Stem Cell Reports. 2021 Sep 14;16(9):2274-2288. doi: 10.1016/j.stemcr.2021.07.012. Epub 2021 Jul 20. Stem Cell Reports. 2021. PMID: 34403650 Free PMC article.