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The TNF-derived TIP peptide activates the epithelial sodium channel and ameliorates experimental nephrotoxic serum nephritis.
Madaio MP, Czikora I, Kvirkvelia N, McMenamin M, Yue Q, Liu T, Toque HA, Sridhar S, Covington K, Alaisami R, O'Connor PM, Caldwell RW, Chen JK, Clauss M, Brands MW, Eaton DC, Romero MJ, Lucas R. Madaio MP, et al. Kidney Int. 2019 Jun;95(6):1359-1372. doi: 10.1016/j.kint.2018.12.022. Epub 2019 Mar 21. Kidney Int. 2019. PMID: 30905471 Free PMC article.
Oral NaHCO3 Activates a Splenic Anti-Inflammatory Pathway: Evidence That Cholinergic Signals Are Transmitted via Mesothelial Cells.
Ray SC, Baban B, Tucker MA, Seaton AJ, Chang KC, Mannon EC, Sun J, Patel B, Wilson K, Musall JB, Ocasio H, Irsik D, Filosa JA, Sullivan JC, Marshall B, Harris RA, O'Connor PM. Ray SC, et al. J Immunol. 2018 May 15;200(10):3568-3586. doi: 10.4049/jimmunol.1701605. Epub 2018 Apr 16. J Immunol. 2018. PMID: 29661827 Free PMC article.
A radical approach to balancing the tides of tubular flow.
O'Connor PM. O'Connor PM. Am J Physiol Renal Physiol. 2014 Oct 15;307(8):F917-8. doi: 10.1152/ajprenal.00436.2014. Epub 2014 Aug 13. Am J Physiol Renal Physiol. 2014. PMID: 25122047 Free PMC article. No abstract available.