R01 DE023685/DE/NIDCR NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2013	8
2014	14
2015	5
2016	4
2017	2
2018	8
2019	7
2020	7
2021	7
2022	3
2023	2
2024	0

1

To Tip or Not to Tip: A New Combination for Precision Medicine in Head and Neck Cancer.

Lee RH, Johnson DE, Grandis JR. Lee RH, et al. Cancer Res. 2023 Oct 2;83(19):3162-3164. doi: 10.1158/0008-5472.CAN-23-1858. Cancer Res. 2023. PMID: 37779427 Free PMC article.

2

The mutational profiles and corresponding therapeutic implications of PI3K mutations in cancer.

VanLandingham NK, Nazarenko A, Grandis JR, Johnson DE. VanLandingham NK, et al. Adv Biol Regul. 2023 Jan;87:100934. doi: 10.1016/j.jbior.2022.100934. Epub 2022 Nov 15. Adv Biol Regul. 2023. PMID: 36402737 Free PMC article. Review.

3

Emerging tyrosine kinase inhibitors for head and neck cancer.

Long Z, Grandis JR, Johnson DE. Long Z, et al. Expert Opin Emerg Drugs. 2022 Sep;27(3):333-344. doi: 10.1080/14728214.2022.2125954. Epub 2022 Sep 21. Expert Opin Emerg Drugs. 2022. PMID: 36131561 Free PMC article. Review.

4

NSAIDs Overcome PIK3CA Mutation-Mediated Resistance to EGFR Inhibition in Head and Neck Cancer Preclinical Models.

Li H, Peyser ND, Zeng Y, Ha PK, Johnson DE, Grandis JR. Li H, et al. Cancers (Basel). 2022 Jan 20;14(3):506. doi: 10.3390/cancers14030506. Cancers (Basel). 2022. PMID: 35158773 Free PMC article.

5

Therapeutic implications of activating noncanonical PIK3CA mutations in head and neck squamous cell carcinoma.

Jin N, Keam B, Cho J, Lee MJ, Kim HR, Torosyan H, Jura N, Ng PK, Mills GB, Li H, Zeng Y, Barbash Z, Tarcic G, Kang H, Bauman JE, Kim MO, VanLandingham NK, Swaney DL, Krogan NJ, Johnson DE, Grandis JR. Jin N, et al. J Clin Invest. 2021 Nov 15;131(22):e150335. doi: 10.1172/JCI150335. J Clin Invest. 2021. PMID: 34779417 Free PMC article.

6

A protein network map of head and neck cancer reveals PIK3CA mutant drug sensitivity.

Swaney DL, Ramms DJ, Wang Z, Park J, Goto Y, Soucheray M, Bhola N, Kim K, Zheng F, Zeng Y, McGregor M, Herrington KA, O'Keefe R, Jin N, VanLandingham NK, Foussard H, Von Dollen J, Bouhaddou M, Jimenez-Morales D, Obernier K, Kreisberg JF, Kim M, Johnson DE, Jura N, Grandis JR, Gutkind JS, Ideker T, Krogan NJ. Swaney DL, et al. Science. 2021 Oct;374(6563):eabf2911. doi: 10.1126/science.abf2911. Epub 2021 Oct 1. Science. 2021. PMID: 34591642 Free PMC article.

7

Caveolin-1 and Sox-2 are predictive biomarkers of cetuximab response in head and neck cancer.

Bouhaddou M, Lee RH, Li H, Bhola NE, O'Keefe RA, Naser M, Zhu TR, Nwachuku K, Duvvuri U, Olshen AB, Roy R, Hechmer A, Bolen J, Keysar SB, Jimeno A, Mills GB, Vandenberg S, Swaney DL, Johnson DE, Krogan NJ, Grandis JR. Bouhaddou M, et al. JCI Insight. 2021 Oct 22;6(20):e151982. doi: 10.1172/jci.insight.151982. JCI Insight. 2021. PMID: 34546978 Free PMC article.

8

IGF2 Mediates Resistance to Isoform-Selective-Inhibitors of the PI3K in HPV Positive Head and Neck Cancer.

Badarni M, Prasad M, Golden A, Bhattacharya B, Levin L, Yegodayev KM, Dimitstein O, Joshua BZ, Cohen L, Khrameeva E, Kong D, Porgador A, Braiman A, Grandis JR, Rotblat B, Elkabets M. Badarni M, et al. Cancers (Basel). 2021 May 7;13(9):2250. doi: 10.3390/cancers13092250. Cancers (Basel). 2021. PMID: 34067117 Free PMC article.

9

Treatment of Fanconi Anemia-Associated Head and Neck Cancer: Opportunities to Improve Outcomes.

Lee RH, Kang H, Yom SS, Smogorzewska A, Johnson DE, Grandis JR. Lee RH, et al. Clin Cancer Res. 2021 Oct 1;27(19):5168-5187. doi: 10.1158/1078-0432.CCR-21-1259. Clin Cancer Res. 2021. PMID: 34045293 Free PMC article.

10

Disruption of the HER3-PI3K-mTOR oncogenic signaling axis and PD-1 blockade as a multimodal precision immunotherapy in head and neck cancer.

Wang Z, Goto Y, Allevato MM, Wu VH, Saddawi-Konefka R, Gilardi M, Alvarado D, Yung BS, O'Farrell A, Molinolo AA, Duvvuri U, Grandis JR, Califano JA, Cohen EEW, Gutkind JS. Wang Z, et al. Nat Commun. 2021 Apr 22;12(1):2383. doi: 10.1038/s41467-021-22619-w. Nat Commun. 2021. PMID: 33888713 Free PMC article.

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