R01 DA047858/DA/NIDA NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2018	1
2019	5
2020	6
2021	11
2022	6
2023	7
2024	1

1

Cannabinoid CB ₂ receptors in primary sensory neurons are implicated in CB ₂ agonist-mediated suppression of paclitaxel-induced neuropathic nociception and sexually-dimorphic sparing of morphine tolerance.

Guenther KG, Lin X, Xu Z, Makriyannis A, Romero J, Hillard CJ, Mackie K, Hohmann AG. Guenther KG, et al. bioRxiv [Preprint]. 2024 Mar 10:2024.03.05.583426. doi: 10.1101/2024.03.05.583426. bioRxiv. 2024. PMID: 38496640 Free PMC article. Preprint.

2

A monoacylglycerol lipase inhibitor showing therapeutic efficacy in mice without central side effects or dependence.

Jiang M, Huizenga MCW, Wirt JL, Paloczi J, Amedi A, van den Berg RJBHN, Benz J, Collin L, Deng H, Di X, Driever WF, Florea BI, Grether U, Janssen APA, Hankemeier T, Heitman LH, Lam TW, Mohr F, Pavlovic A, Ruf I, van den Hurk H, Stevens AF, van der Vliet D, van der Wel T, Wittwer MB, van Boeckel CAA, Pacher P, Hohmann AG, van der Stelt M. Jiang M, et al. Nat Commun. 2023 Dec 5;14(1):8039. doi: 10.1038/s41467-023-43606-3. Nat Commun. 2023. PMID: 38052772 Free PMC article.

3

NAPE-PLD in the ventral tegmental area regulates reward events, feeding and energy homeostasis.

Castel J, Li G, Oriane O, Leishman E, Cani PD, Bradshaw H, Mackie K, Everard A, Luquet S, Gangarossa G. Castel J, et al. Res Sq [Preprint]. 2023 Sep 20:rs.3.rs-3199777. doi: 10.21203/rs.3.rs-3199777/v1. Res Sq. 2023. PMID: 37790425 Free PMC article. Updated. Preprint.

4

Small Molecule Activation of NAPE-PLD Enhances Efferocytosis by Macrophages.

Zarrow JE, Alli-Oluwafuyi AM, Youwakim CM, Kim K, Jenkins AN, Suero IC, Jones MR, Mashhadi Z, Mackie K, Waterson AG, Doran AC, Sulikowski GA, Davies SS. Zarrow JE, et al. ACS Chem Biol. 2023 Aug 18;18(8):1891-1904. doi: 10.1021/acschembio.3c00401. Epub 2023 Aug 2. ACS Chem Biol. 2023. PMID: 37531659 Free article.

5

A collection of cannabinoid-related negative findings from autaptic hippocampal neurons.

Straiker A, Dvorakova M, Bosquez-Berger T, Blahos J, Mackie K. Straiker A, et al. Sci Rep. 2023 Jun 13;13(1):9610. doi: 10.1038/s41598-023-36710-3. Sci Rep. 2023. PMID: 37311900 Free PMC article.

6

Conditional deletion of CB2 cannabinoid receptors from peripheral sensory neurons eliminates CB2-mediated antinociceptive efficacy in a mouse model of carrageenan-induced inflammatory pain.

Guenther KG, Xu Z, Romero J, Hillard CJ, Mackie K, Hohmann AG. Guenther KG, et al. Neuropharmacology. 2023 Oct 1;237:109601. doi: 10.1016/j.neuropharm.2023.109601. Epub 2023 Jun 5. Neuropharmacology. 2023. PMID: 37286073

7

Peripheral sensory neuron CB2 cannabinoid receptors are necessary for both CB2-mediated antinociceptive efficacy and sparing of morphine tolerance in a mouse model of anti-retroviral toxic neuropathy.

Carey LM, Xu Z, Rajic G, Makriyannis A, Romero J, Hillard C, Mackie K, Hohmann AG. Carey LM, et al. Pharmacol Res. 2023 Jan;187:106560. doi: 10.1016/j.phrs.2022.106560. Epub 2022 Nov 20. Pharmacol Res. 2023. PMID: 36417942 Free PMC article.

8

Negative allosteric modulation of CB₁ cannabinoid receptor signaling suppresses opioid-mediated reward.

Iyer V, Rangel-Barajas C, Woodward TJ, Kulkarni A, Cantwell L, Crystal JD, Mackie K, Rebec GV, Thakur GA, Hohmann AG. Iyer V, et al. Pharmacol Res. 2022 Nov;185:106474. doi: 10.1016/j.phrs.2022.106474. Epub 2022 Sep 28. Pharmacol Res. 2022. PMID: 36179954 Free PMC article.

9

Inhibition of PSD95-nNOS protein-protein interactions decreases morphine reward and relapse vulnerability in rats.

Oliva I, Saberi SA, Rangel-Barajas C, Iyer V, Bunner KD, Lai YY, Kulkarni PM, Garai S, Thakur GA, Crystal JD, Rebec GV, Hohmann AG. Oliva I, et al. Addict Biol. 2022 Sep;27(5):e13220. doi: 10.1111/adb.13220. Addict Biol. 2022. PMID: 36001441 Free PMC article.

10

A peripheral CB2 cannabinoid receptor mechanism suppresses chemotherapy-induced peripheral neuropathy: evidence from a CB2 reporter mouse.

Lin X, Xu Z, Carey L, Romero J, Makriyannis A, Hillard CJ, Ruggiero E, Dockum M, Houk G, Mackie K, Albrecht PJ, Rice FL, Hohmann AG. Lin X, et al. Pain. 2022 May 1;163(5):834-851. doi: 10.1097/j.pain.0000000000002502. Pain. 2022. PMID: 35001054 Free PMC article.

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