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Targeting Myc-driven stress addiction in colorectal cancer.
Saeed H, Leibowitz BJ, Zhang L, Yu J. Saeed H, et al. Drug Resist Updat. 2023 Jul;69:100963. doi: 10.1016/j.drup.2023.100963. Epub 2023 Apr 20. Drug Resist Updat. 2023. PMID: 37119690 Free PMC article. Review.
Release of Interferon-β (IFN-β) from Probiotic Limosilactobacillus reuteri-IFN-β (LR-IFN-β) Mitigates Gastrointestinal Acute Radiation Syndrome (GI-ARS) following Whole Abdominal Irradiation.
Hamade DF, Epperly MW, Fisher R, Hou W, Shields D, van Pijkeren JP, Mukherjee A, Yu J, Leibowitz BJ, Vlad AM, Coffman L, Wang H, Huq MS, Huang Z, Rogers CJ, Greenberger JS. Hamade DF, et al. Cancers (Basel). 2023 Mar 8;15(6):1670. doi: 10.3390/cancers15061670. Cancers (Basel). 2023. PMID: 36980556 Free PMC article.
Intestinal Radiation Protection and Mitigation by Second-Generation Probiotic Lactobacillus-reuteri Engineered to Deliver Interleukin-22.
Espinal A, Epperly MW, Mukherjee A, Fisher R, Shields D, Wang H, Huq MS, Hamade DF, Vlad AM, Coffman L, Buckanovich R, Yu J, Leibowitz BJ, van Pijkeren JP, Patel RB, Stolz D, Watkins S, Ejaz A, Greenberger JS. Espinal A, et al. Int J Mol Sci. 2022 May 17;23(10):5616. doi: 10.3390/ijms23105616. Int J Mol Sci. 2022. PMID: 35628427 Free PMC article.
Lactobacillus reuteri Releasing IL-22 (LR-IL-22) Facilitates Intestinal Radioprotection for Whole-Abdomen Irradiation (WAI) of Ovarian Cancer.
Hamade DF, Espinal A, Yu J, Leibowitz BJ, Fisher R, Hou W, Shields D, van Pijkeren JP, Mukherjee A, Epperly MW, Vlad AM, Coffman L, Wang H, Saiful Huq M, Patel R, Huang J, Greenberger JS. Hamade DF, et al. Radiat Res. 2022 Jul 1;198(1):89-105. doi: 10.1667/RADE-21-00224.1. Radiat Res. 2022. PMID: 35446961 Free PMC article.
Interferon b drives intestinal regeneration after radiation.
Leibowitz BJ, Zhao G, Wei L, Ruan H, Epperly M, Chen L, Lu X, Greenberger JS, Zhang L, Yu J. Leibowitz BJ, et al. Sci Adv. 2021 Oct 8;7(41):eabi5253. doi: 10.1126/sciadv.abi5253. Epub 2021 Oct 6. Sci Adv. 2021. PMID: 34613772 Free PMC article.