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2020 9
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Direct interaction with the BRD4 carboxyl-terminal motif (CTM) and TopBP1 is required for human papillomavirus 16 E2 association with mitotic chromatin and plasmid segregation function.
Prabhakar AT, James CD, Fontan CT, Otoa R, Wang X, Bristol ML, Yeager C, Hill RD, Dubey A, Wu S-Y, Chiang C-M, Morgan IM. Prabhakar AT, et al. J Virol. 2023 Oct 31;97(10):e0078223. doi: 10.1128/jvi.00782-23. Epub 2023 Sep 15. J Virol. 2023. PMID: 37712702 Free PMC article.
Loss of BRD4 induces cell senescence in HSC/HPCs by deregulating histone H3 clipping.
Yang H, Sui P, Guo Y, Chen S, Maloof ME, Ge G, Nihozeko F, Delma CR, Zhu G, Zhang P, Ye Z, Medina EA, Ayad NG, Mesa R, Nimer SD, Chiang CM, Xu M, Chen Y, Yang FC. Yang H, et al. EMBO Rep. 2023 Oct 9;24(10):e57032. doi: 10.15252/embr.202357032. Epub 2023 Aug 31. EMBO Rep. 2023. PMID: 37650863 Free article.
EGFR ligand shifts the role of EGFR from oncogene to tumour suppressor in EGFR-amplified glioblastoma by suppressing invasion through BIN3 upregulation.
Guo G, Gong K, Beckley N, Zhang Y, Yang X, Chkheidze R, Hatanpaa KJ, Garzon-Muvdi T, Koduru P, Nayab A, Jenks J, Sathe AA, Liu Y, Xing C, Wu SY, Chiang CM, Mukherjee B, Burma S, Wohlfeld B, Patel T, Mickey B, Abdullah K, Youssef M, Pan E, Gerber DE, Tian S, Sarkaria JN, McBrayer SK, Zhao D, Habib AA. Guo G, et al. Nat Cell Biol. 2022 Aug;24(8):1291-1305. doi: 10.1038/s41556-022-00962-4. Epub 2022 Aug 1. Nat Cell Biol. 2022. PMID: 35915159 Free PMC article.
Targeting ESR1 mutation-induced transcriptional addiction in breast cancer with BET inhibition.
Udden SN, Wang Q, Kumar S, Malladi VS, Wu SY, Wei S, Posner BA, Geboers S, Williams NS, Liu Y, Sharma JK, Mani RS, Malladi S, Parra K, Hofstad M, Raj GV, Larios JM, Jagsi R, Wicha MS, Park BH, Gupta GP, Chinnaiyan AM, Chiang CM, Alluri PG. Udden SN, et al. JCI Insight. 2022 Sep 8;7(17):e151851. doi: 10.1172/jci.insight.151851. JCI Insight. 2022. PMID: 35881485 Free PMC article.
26 results