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SARS-CoV-2 replication in airway epithelia requires motile cilia and microvillar reprogramming.
Wu CT, Lidsky PV, Xiao Y, Cheng R, Lee IT, Nakayama T, Jiang S, He W, Demeter J, Knight MG, Turn RE, Rojas-Hernandez LS, Ye C, Chiem K, Shon J, Martinez-Sobrido L, Bertozzi CR, Nolan GP, Nayak JV, Milla C, Andino R, Jackson PK. Wu CT, et al. Cell. 2023 Jan 5;186(1):112-130.e20. doi: 10.1016/j.cell.2022.11.030. Epub 2022 Dec 2. Cell. 2023. PMID: 36580912 Free PMC article.
Oxaliplatin disrupts nucleolar function through biophysical disintegration.
Schmidt HB, Jaafar ZA, Wulff BE, Rodencal JJ, Hong K, Aziz-Zanjani MO, Jackson PK, Leonetti MD, Dixon SJ, Rohatgi R, Brandman O. Schmidt HB, et al. Cell Rep. 2022 Nov 8;41(6):111629. doi: 10.1016/j.celrep.2022.111629. Cell Rep. 2022. PMID: 36351392 Free PMC article.
The Mettl3 epitranscriptomic writer amplifies p53 stress responses.
Raj N, Wang M, Seoane JA, Zhao RL, Kaiser AM, Moonie NA, Demeter J, Boutelle AM, Kerr CH, Mulligan AS, Moffatt C, Zeng SX, Lu H, Barna M, Curtis C, Chang HY, Jackson PK, Attardi LD. Raj N, et al. Mol Cell. 2022 Jul 7;82(13):2370-2384.e10. doi: 10.1016/j.molcel.2022.04.010. Epub 2022 May 4. Mol Cell. 2022. PMID: 35512709 Free PMC article.
Structured elements drive extensive circular RNA translation.
Chen CK, Cheng R, Demeter J, Chen J, Weingarten-Gabbay S, Jiang L, Snyder MP, Weissman JS, Segal E, Jackson PK, Chang HY. Chen CK, et al. Mol Cell. 2021 Oct 21;81(20):4300-4318.e13. doi: 10.1016/j.molcel.2021.07.042. Epub 2021 Aug 25. Mol Cell. 2021. PMID: 34437836 Free PMC article.