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2020 1
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2023 5
2024 0

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ALK inhibitors increase ALK expression and sensitize neuroblastoma cells to ALK.CAR-T cells.
Bergaggio E, Tai WT, Aroldi A, Mecca C, Landoni E, Nüesch M, Mota I, Metovic J, Molinaro L, Ma L, Alvarado D, Ambrogio C, Voena C, Blasco RB, Li T, Klein D, Irvine DJ, Papotti M, Savoldo B, Dotti G, Chiarle R. Bergaggio E, et al. Cancer Cell. 2023 Dec 11;41(12):2100-2116.e10. doi: 10.1016/j.ccell.2023.11.004. Epub 2023 Nov 30. Cancer Cell. 2023. PMID: 38039964
Biomaterials-Mediated Engineering of the Immune System.
Backlund C, Jalili-Firoozinezhad S, Kim B, Irvine DJ. Backlund C, et al. Annu Rev Immunol. 2023 Apr 26;41:153-179. doi: 10.1146/annurev-immunol-101721-040259. Epub 2023 Jan 25. Annu Rev Immunol. 2023. PMID: 36696570 Free PMC article. Review.
The future of engineered immune cell therapies.
Irvine DJ, Maus MV, Mooney DJ, Wong WW. Irvine DJ, et al. Science. 2022 Nov 25;378(6622):853-858. doi: 10.1126/science.abq6990. Epub 2022 Nov 24. Science. 2022. PMID: 36423279 Free PMC article. Review.
Screening for CD19-specific chimaeric antigen receptors with enhanced signalling via a barcoded library of intracellular domains.
Gordon KS, Kyung T, Perez CR, Holec PV, Ramos A, Zhang AQ, Agarwal Y, Liu Y, Koch CE, Starchenko A, Joughin BA, Lauffenburger DA, Irvine DJ, Hemann MT, Birnbaum ME. Gordon KS, et al. Nat Biomed Eng. 2022 Jul;6(7):855-866. doi: 10.1038/s41551-022-00896-0. Epub 2022 Jun 16. Nat Biomed Eng. 2022. PMID: 35710755 Free PMC article.
Controlling timing and location in vaccines.
Irvine DJ, Aung A, Silva M. Irvine DJ, et al. Adv Drug Deliv Rev. 2020;158:91-115. doi: 10.1016/j.addr.2020.06.019. Epub 2020 Jun 26. Adv Drug Deliv Rev. 2020. PMID: 32598970 Free PMC article.