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Structural basis for self-discrimination by neoantigen-specific TCRs.
Finnigan JP, Newman JH, Patskovsky Y, Patskovska L, Ishizuka AS, Lynn GM, Seder RA, Krogsgaard M, Bhardwaj N. Finnigan JP, et al. Nat Commun. 2024 Mar 8;15(1):2140. doi: 10.1038/s41467-024-46367-9. Nat Commun. 2024. PMID: 38459027 Free PMC article.
Safety and effectiveness of combination versus monotherapy with immune checkpoint inhibitors in patients with preexisting autoimmune diseases.
Reid P, Sandigursky S, Song J, Lopez-Olivo MA, Safa H, Cytryn S, Efuni E, Buni M, Pavlick A, Krogsgaard M, Abu-Shawer O, Altan M, Weber JS, Rahma OE, Suarez-Almazor ME, Diab A, Abdel-Wahab N. Reid P, et al. Oncoimmunology. 2023 Oct 30;12(1):2261264. doi: 10.1080/2162402X.2023.2261264. eCollection 2023. Oncoimmunology. 2023. PMID: 38126033 Free PMC article.
Mechanical force regulates ligand binding and function of PD-1.
Li K, Cardenas-Lizana P, Kellner AV, Yuan Z, Ahn E, Lyu J, Li Z, Salaita K, Ahmed R, Zhu C. Li K, et al. bioRxiv [Preprint]. 2023 Aug 15:2023.08.13.553152. doi: 10.1101/2023.08.13.553152. bioRxiv. 2023. PMID: 37645980 Free PMC article. Preprint.
Molecular mechanism of phosphopeptide neoantigen immunogenicity.
Patskovsky Y, Natarajan A, Patskovska L, Nyovanie S, Joshi B, Morin B, Brittsan C, Huber O, Gordon S, Michelet X, Schmitzberger F, Stein RB, Findeis MA, Hurwitz A, Van Dijk M, Chantzoura E, Yague AS, Pollack Smith D, Buell JS, Underwood D, Krogsgaard M. Patskovsky Y, et al. Nat Commun. 2023 Jun 23;14(1):3763. doi: 10.1038/s41467-023-39425-1. Nat Commun. 2023. PMID: 37353482 Free PMC article.
Prior anti-CTLA-4 therapy impacts molecular characteristics associated with anti-PD-1 response in advanced melanoma.
Campbell KM, Amouzgar M, Pfeiffer SM, Howes TR, Medina E, Travers M, Steiner G, Weber JS, Wolchok JD, Larkin J, Hodi FS, Boffo S, Salvador L, Tenney D, Tang T, Thompson MA, Spencer CN, Wells DK, Ribas A. Campbell KM, et al. Cancer Cell. 2023 Apr 10;41(4):791-806.e4. doi: 10.1016/j.ccell.2023.03.010. Cancer Cell. 2023. PMID: 37037616 Free PMC article.
Structural Basis for Self-Discrimination by Neoantigen-Specific TCRs.
Finnigan JP, Newman JH, Patskovsky Y, Patskovska L, Ishizuka AS, Lynn GM, Seder RA, Krogsgaard M, Bhardwaj N. Finnigan JP, et al. Res Sq [Preprint]. 2023 Jan 31:rs.3.rs-2531184. doi: 10.21203/rs.3.rs-2531184/v1. Res Sq. 2023. PMID: 36778273 Free PMC article. Updated. Preprint.