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Page 1
Metabolic orchestration of cell death by AMPK-mediated phosphorylation of RIPK1.
Zhang T, Xu D, Trefts E, Lv M, Inuzuka H, Song G, Liu M, Lu J, Liu J, Chu C, Wang M, Wang H, Meng H, Liu H, Zhuang Y, Xie X, Dang F, Guan D, Men Y, Jiang S, Jiang C, Dai X, Liu J, Wang Z, Yan P, Wang J, Tu Z, Babuta M, Erickson E, Hillis AL, Dibble CC, Asara JM, Szabo G, Sicinski P, Miao J, Lee YR, Pan L, Shaw RJ, Yuan J, Wei W. Zhang T, et al. Science. 2023 Jun 30;380(6652):1372-1380. doi: 10.1126/science.abn1725. Epub 2023 Jun 29. Science. 2023. PMID: 37384704 Free PMC article.
Cyclin E in normal physiology and disease states.
Chu C, Geng Y, Zhou Y, Sicinski P. Chu C, et al. Trends Cell Biol. 2021 Sep;31(9):732-746. doi: 10.1016/j.tcb.2021.05.001. Epub 2021 May 27. Trends Cell Biol. 2021. PMID: 34052101 Free PMC article. Review.
Targeting the cyclin-dependent kinase 5 in metastatic melanoma.
Sharma S, Zhang T, Michowski W, Rebecca VW, Xiao M, Ferretti R, Suski JM, Bronson RT, Paulo JA, Frederick D, Fassl A, Boland GM, Geng Y, Lees JA, Medema RH, Herlyn M, Gygi SP, Sicinski P. Sharma S, et al. Proc Natl Acad Sci U S A. 2020 Apr 7;117(14):8001-8012. doi: 10.1073/pnas.1912617117. Epub 2020 Mar 19. Proc Natl Acad Sci U S A. 2020. PMID: 32193336 Free PMC article.
A mitotic CDK5-PP4 phospho-signaling cascade primes 53BP1 for DNA repair in G1.
Zheng XF, Acharya SS, Choe KN, Nikhil K, Adelmant G, Satapathy SR, Sharma S, Viccaro K, Rana S, Natarajan A, Sicinski P, Marto JA, Shah K, Chowdhury D. Zheng XF, et al. Nat Commun. 2019 Sep 18;10(1):4252. doi: 10.1038/s41467-019-12084-x. Nat Commun. 2019. PMID: 31534152 Free PMC article.