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Page 1
Multiparatopic antibodies induce targeted downregulation of programmed death-ligand 1.
Ludwig SD, Meksiriporn B, Tan J, Kureshi R, Mishra A, Kaeo KJ, Zhu A, Stavrakis G, Lee SJ, Schodt DJ, Wester MJ, Kumar D, Lidke KA, Cox AL, Dooley HM, Nimmagadda S, Spangler JB. Ludwig SD, et al. Cell Chem Biol. 2024 Mar 27:S2451-9456(24)00088-6. doi: 10.1016/j.chembiol.2024.02.014. Online ahead of print. Cell Chem Biol. 2024. PMID: 38547863
Decoupling FcRn and tumor contributions to elevated immune checkpoint inhibitor clearance in cancer cachexia.
Vu TT, Kim K, Manna M, Thomas J, Remaily BC, Montgomery EJ, Costa T, Granchie L, Xie Z, Guo Y, Chen M, Castillo AMM, Kulp SK, Mo X, Nimmagadda S, Gregorevic P, Owen DH, Ganesan LP, Mace TA, Coss CC, Phelps MA. Vu TT, et al. Pharmacol Res. 2024 Jan;199:107048. doi: 10.1016/j.phrs.2023.107048. Epub 2023 Dec 23. Pharmacol Res. 2024. PMID: 38145833 Free PMC article.
PD-L1 near Infrared Photoimmunotherapy of Ovarian Cancer Model.
Jin J, Sivakumar I, Mironchik Y, Krishnamachary B, Wildes F, Barnett JD, Hung CF, Nimmagadda S, Kobayashi H, Bhujwalla ZM, Penet MF. Jin J, et al. Cancers (Basel). 2022 Jan 26;14(3):619. doi: 10.3390/cancers14030619. Cancers (Basel). 2022. PMID: 35158887 Free PMC article.
Pharmacodynamic measures within tumors expose differential activity of PD(L)-1 antibody therapeutics.
Kumar D, Mishra A, Lisok A, Kureshi R, Shelake S, Plyku D, Sen R, Doucet M, De Silva RA, Mease RC, Forde PM, Jaffee EM, Desai P, Ganguly S, Gabrielson E, Vaidya D, Spangler JB, Nimmagadda S. Kumar D, et al. Proc Natl Acad Sci U S A. 2021 Sep 14;118(37):e2107982118. doi: 10.1073/pnas.2107982118. Proc Natl Acad Sci U S A. 2021. PMID: 34508005 Free PMC article.
15 results