R01 CA232347/CA/NCI NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2018	1
2020	5
2021	3
2023	6
2024	0

1

CRISPR screening identifies the deubiquitylase ATXN3 as a PD-L1-positive regulator for tumor immune evasion.

Wang S, Iyer R, Han X, Wei J, Li N, Cheng Y, Zhou Y, Gao Q, Zhang L, Yan M, Sun Z, Fang D. Wang S, et al. J Clin Invest. 2023 Dec 1;133(23):e167728. doi: 10.1172/JCI167728. J Clin Invest. 2023. PMID: 38038129 Free PMC article.

2

ATXN3 deubiquitinates YAP1 to promote tumor growth.

Wang S, Liu K, Han X, Cheng Y, Zhao E, Brat DJ, Sun Z, Fang D. Wang S, et al. Am J Cancer Res. 2023 Sep 15;13(9):4222-4234. eCollection 2023. Am J Cancer Res. 2023. PMID: 37818078 Free PMC article.

3

Ubiquitin-specific peptidase 22 controls integrin-dependent cancer cell stemness and metastasis.

Liu K, Gao Q, Jia Y, Wei J, Chaudhuri S, Wang S, Tang A, Mani N, Iyer R, Cheng Y, Gao B, Lu W, Sun Z, Liu H, Fang D. Liu K, et al. Res Sq [Preprint]. 2023 Jun 16:rs.3.rs-2922367. doi: 10.21203/rs.3.rs-2922367/v1. Res Sq. 2023. PMID: 37398311 Free PMC article. Preprint.

4

Unique molecular signatures sustained in circulating monocytes and regulatory T cells in convalescent COVID-19 patients.

Hoffmann AD, Weinberg SE, Swaminathan S, Chaudhuri S, Almubarak HF, Schipma MJ, Mao C, Wang X, El-Shennawy L, Dashzeveg NK, Wei J, Mehl PJ, Shihadah LJ, Wai CM, Ostiguin C, Jia Y, D'Amico P, Wang NR, Luo Y, Demonbreun AR, Ison MG, Liu H, Fang D. Hoffmann AD, et al. Clin Immunol. 2023 Jul;252:109634. doi: 10.1016/j.clim.2023.109634. Epub 2023 May 5. Clin Immunol. 2023. PMID: 37150240 Free PMC article.

5

scRNA-Seq and imaging mass cytometry analyses unveil iNKT cells-mediated anti-tumor immunity in pancreatic cancer liver metastasis.

Yi Q, Wang J, Liu T, Yao Y, Loveless I, Subedi K, Toor J, Adrianto I, Xiao H, Chen B, Crawford HC, Fang D, Zhou L, Mi QS. Yi Q, et al. Cancer Lett. 2023 May 1;561:216149. doi: 10.1016/j.canlet.2023.216149. Epub 2023 Mar 27. Cancer Lett. 2023. PMID: 36990268

6

Hepatic SEL1L-HRD1 ER-associated degradation regulates systemic iron homeostasis via ceruloplasmin.

Thepsuwan P, Bhattacharya A, Song Z, Hippleheuser S, Feng S, Wei X, Das NK, Sierra M, Wei J, Fang D, Huang YM, Zhang K, Shah YM, Sun S. Thepsuwan P, et al. Proc Natl Acad Sci U S A. 2023 Jan 10;120(2):e2212644120. doi: 10.1073/pnas.2212644120. Epub 2023 Jan 3. Proc Natl Acad Sci U S A. 2023. PMID: 36595688 Free PMC article.

7

HRD1-mediated METTL14 degradation regulates m⁶A mRNA modification to suppress ER proteotoxic liver disease.

Wei J, Harada BT, Lu D, Ma R, Gao B, Xu Y, Montauti E, Mani N, Chaudhuri SM, Gregory S, Weinberg SE, Zhang DD, Green R, He C, Fang D. Wei J, et al. Mol Cell. 2021 Dec 16;81(24):5052-5065.e6. doi: 10.1016/j.molcel.2021.10.028. Epub 2021 Nov 29. Mol Cell. 2021. PMID: 34847358 Free PMC article.

8

Inositol-Requiring Enzyme 1α-Mediated Synthesis of Monounsaturated Fatty Acids as a Driver of B Cell Differentiation and Lupus-like Autoimmune Disease.

Zhang Y, Gui M, Wang Y, Mani N, Chaudhuri S, Gao B, Li H, Kanwar YS, Lewis SA, Dumas SN, Ntambi JM, Zhang K, Fang D. Zhang Y, et al. Arthritis Rheumatol. 2021 Dec;73(12):2314-2326. doi: 10.1002/art.41883. Epub 2021 Nov 2. Arthritis Rheumatol. 2021. PMID: 34105254 Free PMC article.

9

Regulation of hepatic circadian metabolism by the E3 ubiquitin ligase HRD1-controlled CREBH/PPARα transcriptional program.

Kim H, Wei J, Song Z, Mottillo E, Samavati L, Zhang R, Li L, Chen X, Jena BP, Lin JD, Fang D, Zhang K. Kim H, et al. Mol Metab. 2021 Jul;49:101192. doi: 10.1016/j.molmet.2021.101192. Epub 2021 Feb 13. Mol Metab. 2021. PMID: 33592335 Free PMC article.

10

CRISPR screen in regulatory T cells reveals modulators of Foxp3.

Cortez JT, Montauti E, Shifrut E, Gatchalian J, Zhang Y, Shaked O, Xu Y, Roth TL, Simeonov DR, Zhang Y, Chen S, Li Z, Woo JM, Ho J, Vogel IA, Prator GY, Zhang B, Lee Y, Sun Z, Ifergan I, Van Gool F, Hargreaves DC, Bluestone JA, Marson A, Fang D. Cortez JT, et al. Nature. 2020 Jun;582(7812):416-420. doi: 10.1038/s41586-020-2246-4. Epub 2020 Apr 29. Nature. 2020. PMID: 32499641 Free PMC article.

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