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Engineered immunomodulatory extracellular vesicles derived from epithelial cells acquire capacity for positive and negative T cell co-stimulation in cancer and autoimmunity.
Kugeratski FG, LeBleu VS, Dowlatshahi DP, Sugimoto H, Arian KA, Fan Y, Huang L, Wells D, Lilla S, Hodge K, Zanivan S, McAndrews KM, Kalluri R. Kugeratski FG, et al. bioRxiv [Preprint]. 2023 Nov 4:2023.11.02.565371. doi: 10.1101/2023.11.02.565371. bioRxiv. 2023. PMID: 37961535 Free PMC article. Preprint.
The role of extracellular vesicles in cancer.
Kalluri R, McAndrews KM. Kalluri R, et al. Cell. 2023 Apr 13;186(8):1610-1626. doi: 10.1016/j.cell.2023.03.010. Cell. 2023. PMID: 37059067 Free PMC article. Review.
Estimation of tumor cell total mRNA expression in 15 cancer types predicts disease progression.
Cao S, Wang JR, Ji S, Yang P, Dai Y, Guo S, Montierth MD, Shen JP, Zhao X, Chen J, Lee JJ, Guerrero PA, Spetsieris N, Engedal N, Taavitsainen S, Yu K, Livingstone J, Bhandari V, Hubert SM, Daw NC, Futreal PA, Efstathiou E, Lim B, Viale A, Zhang J, Nykter M, Czerniak BA, Brown PH, Swanton C, Msaouel P, Maitra A, Kopetz S, Campbell P, Speed TP, Boutros PC, Zhu H, Urbanucci A, Demeulemeester J, Van Loo P, Wang W. Cao S, et al. Nat Biotechnol. 2022 Nov;40(11):1624-1633. doi: 10.1038/s41587-022-01342-x. Epub 2022 Jun 13. Nat Biotechnol. 2022. PMID: 35697807 Free PMC article.
Unique somatic variants in DNA from urine exosomes of individuals with bladder cancer.
Zhou X, Kurywchak P, Wolf-Dennen K, Che SPY, Sulakhe D, D'Souza M, Xie B, Maltsev N, Gilliam TC, Wu CC, McAndrews KM, LeBleu VS, McConkey DJ, Volpert OV, Pretzsch SM, Czerniak BA, Dinney CP, Kalluri R. Zhou X, et al. Mol Ther Methods Clin Dev. 2021 May 29;22:360-376. doi: 10.1016/j.omtm.2021.05.010. eCollection 2021 Sep 10. Mol Ther Methods Clin Dev. 2021. PMID: 34514028 Free PMC article.