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RNA-binding protein FXR1 drives cMYC translation by recruiting eIF4F complex to the translation start site.
George J, Li Y, Kadamberi IP, Parashar D, Tsaih SW, Gupta P, Geethadevi A, Chen C, Ghosh C, Sun Y, Mittal S, Ramchandran R, Rui H, Lopez-Berestein G, Rodriguez-Aguayo C, Leone G, Rader JS, Sood AK, Dey M, Pradeep S, Chaluvally-Raghavan P. George J, et al. Cell Rep. 2023 Mar 28;42(3):112228. doi: 10.1016/j.celrep.2023.112228. Epub 2023 Mar 7. Cell Rep. 2023. PMID: 36884347 Free PMC article. No abstract available.
Tumor Derived Extracellular Vesicles Drive T Cell Exhaustion in Tumor Microenvironment through Sphingosine Mediated Signaling and Impacting Immunotherapy Outcomes in Ovarian Cancer.
Gupta P, Kadamberi IP, Mittal S, Tsaih SW, George J, Kumar S, Vijayan DK, Geethadevi A, Parashar D, Topchyan P, McAlarnen L, Volkman BF, Cui W, Zhang KYJ, Di Vizio D, Chaluvally-Raghavan P, Pradeep S. Gupta P, et al. Adv Sci (Weinh). 2022 May;9(14):e2104452. doi: 10.1002/advs.202104452. Epub 2022 Mar 15. Adv Sci (Weinh). 2022. PMID: 35289120 Free PMC article.
RNA-binding protein FXR1 drives cMYC translation by recruiting eIF4F complex to the translation start site.
George J, Li Y, Kadamberi IP, Parashar D, Tsaih SW, Gupta P, Geethadevi A, Chen C, Ghosh C, Sun Y, Mittal S, Ramchandran R, Rui H, Lopez-Berestein G, Rodriguez-Aguayo C, Leone G, Rader JS, Sood AK, Dey M, Pradeep S, Chaluvally-Raghavan P. George J, et al. Cell Rep. 2021 Nov 2;37(5):109934. doi: 10.1016/j.celrep.2021.109934. Cell Rep. 2021. PMID: 34731628 Free PMC article.
Oncostatin M Receptor-Targeted Antibodies Suppress STAT3 Signaling and Inhibit Ovarian Cancer Growth.
Geethadevi A, Nair A, Parashar D, Ku Z, Xiong W, Deng H, Li Y, George J, McAllister DM, Sun Y, Kadamberi IP, Gupta P, Dwinell MB, Bradley WH, Rader JS, Rui H, Schwabe RF, Zhang N, Pradeep S, An Z, Chaluvally-Raghavan P. Geethadevi A, et al. Cancer Res. 2021 Oct 15;81(20):5336-5352. doi: 10.1158/0008-5472.CAN-21-0483. Epub 2021 Aug 11. Cancer Res. 2021. PMID: 34380633 Free PMC article.
Peritoneal Spread of Ovarian Cancer Harbors Therapeutic Vulnerabilities Regulated by FOXM1 and EGFR/ERBB2 Signaling.
Parashar D, Nair B, Geethadevi A, George J, Nair A, Tsaih SW, Kadamberi IP, Gopinadhan Nair GK, Lu Y, Ramchandran R, Uyar DS, Rader JS, Ram PT, Mills GB, Pradeep S, Chaluvally-Raghavan P. Parashar D, et al. Cancer Res. 2020 Dec 15;80(24):5554-5568. doi: 10.1158/0008-5472.CAN-19-3717. Epub 2020 Oct 21. Cancer Res. 2020. PMID: 33087324 Free PMC article.
miRNA551b-3p Activates an Oncostatin Signaling Module for the Progression of Triple-Negative Breast Cancer.
Parashar D, Geethadevi A, Aure MR, Mishra J, George J, Chen C, Mishra MK, Tahiri A, Zhao W, Nair B, Lu Y, Mangala LS, Rodriguez-Aguayo C, Lopez-Berestein G, Camara AKS, Liang M, Rader JS, Ramchandran R, You M, Sood AK, Kristensen VN, Mills GB, Pradeep S, Chaluvally-Raghavan P. Parashar D, et al. Cell Rep. 2019 Dec 24;29(13):4389-4406.e10. doi: 10.1016/j.celrep.2019.11.085. Cell Rep. 2019. PMID: 31875548 Free PMC article.