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2019 1
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2022 7
2024 0

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12 results

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Page 1
An FDA-Approved Antifungal, Ketoconazole, and Its Novel Derivative Suppress tGLI1-Mediated Breast Cancer Brain Metastasis by Inhibiting the DNA-Binding Activity of Brain Metastasis-Promoting Transcription Factor tGLI1.
Doheny D, Manore S, Sirkisoon SR, Zhu D, Aguayo NR, Harrison A, Najjar M, Anguelov M, Cox AO, Furdui CM, Watabe K, Hollis T, Thomas A, Strowd R, Lo HW. Doheny D, et al. Cancers (Basel). 2022 Aug 31;14(17):4256. doi: 10.3390/cancers14174256. Cancers (Basel). 2022. PMID: 36077791 Free PMC article.
Breast cancer extracellular vesicles-derived miR-1290 activates astrocytes in the brain metastatic microenvironment via the FOXA2→CNTF axis to promote progression of brain metastases.
Sirkisoon SR, Wong GL, Aguayo NR, Doheny DL, Zhu D, Regua AT, Arrigo A, Manore SG, Wagner C, Thomas A, Singh R, Xing F, Jin G, Watabe K, Lo HW. Sirkisoon SR, et al. Cancer Lett. 2022 Aug 1;540:215726. doi: 10.1016/j.canlet.2022.215726. Epub 2022 May 16. Cancer Lett. 2022. PMID: 35589002 Free PMC article.
NEDD4 degrades TUSC2 to promote glioblastoma progression.
Rimkus TK, Arrigo AB, Zhu D, Carpenter RL, Sirkisoon S, Doheny D, Regua AT, Wong GL, Manore S, Wagner C, Lin HK, Jin G, Ruiz J, Chan M, Debinski W, Lo HW. Rimkus TK, et al. Cancer Lett. 2022 Apr 10;531:124-135. doi: 10.1016/j.canlet.2022.01.029. Epub 2022 Feb 12. Cancer Lett. 2022. PMID: 35167936 Free PMC article.
Transgenic mouse models of breast cancer.
Regua AT, Arrigo A, Doheny D, Wong GL, Lo HW. Regua AT, et al. Cancer Lett. 2021 Sep 28;516:73-83. doi: 10.1016/j.canlet.2021.05.027. Epub 2021 Jun 6. Cancer Lett. 2021. PMID: 34090924 Free PMC article.
TrkA Interacts with and Phosphorylates STAT3 to Enhance Gene Transcription and Promote Breast Cancer Stem Cells in Triple-Negative and HER2-Enriched Breast Cancers.
Regua AT, Aguayo NR, Jalboush SA, Doheny DL, Manore SG, Zhu D, Wong GL, Arrigo A, Wagner CJ, Yu Y, Thomas A, Chan MD, Ruiz J, Jin G, Strowd R, Sun P, Lin J, Lo HW. Regua AT, et al. Cancers (Basel). 2021 May 12;13(10):2340. doi: 10.3390/cancers13102340. Cancers (Basel). 2021. PMID: 34066153 Free PMC article.
Hedgehog Signaling and Truncated GLI1 in Cancer.
Doheny D, Manore SG, Wong GL, Lo HW. Doheny D, et al. Cells. 2020 Sep 17;9(9):2114. doi: 10.3390/cells9092114. Cells. 2020. PMID: 32957513 Free PMC article. Review.
12 results