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2016 3
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Deregulated DNA ADP-ribosylation impairs telomere replication.
Wondisford AR, Lee J, Lu R, Schuller M, Groslambert J, Bhargava R, Schamus-Haynes S, Cespedes LC, Opresko PL, Pickett HA, Min J, Ahel I, O'Sullivan RJ. Wondisford AR, et al. Nat Struct Mol Biol. 2024 May 7. doi: 10.1038/s41594-024-01279-6. Online ahead of print. Nat Struct Mol Biol. 2024. PMID: 38714889
The interplay of TARG1 and PARG protects against genomic instability.
Groslambert J, Prokhorova E, Wondisford AR, Tromans-Coia C, Giansanti C, Jansen J, Timinszky G, Dobbelstein M, Ahel D, O'Sullivan RJ, Ahel I. Groslambert J, et al. Cell Rep. 2023 Sep 26;42(9):113113. doi: 10.1016/j.celrep.2023.113113. Epub 2023 Sep 6. Cell Rep. 2023. PMID: 37676774 Free PMC article.
Modular antibodies reveal DNA damage-induced mono-ADP-ribosylation as a second wave of PARP1 signaling.
Longarini EJ, Dauben H, Locatelli C, Wondisford AR, Smith R, Muench C, Kolvenbach A, Lynskey ML, Pope A, Bonfiglio JJ, Jurado EP, Fajka-Boja R, Colby T, Schuller M, Ahel I, Timinszky G, O'Sullivan RJ, Huet S, Matic I. Longarini EJ, et al. Mol Cell. 2023 May 18;83(10):1743-1760.e11. doi: 10.1016/j.molcel.2023.03.027. Epub 2023 Apr 27. Mol Cell. 2023. PMID: 37116497 Free PMC article.
RAD51AP1 regulates ALT-HDR through chromatin-directed homeostasis of TERRA.
Kaminski N, Wondisford AR, Kwon Y, Lynskey ML, Bhargava R, Barroso-González J, García-Expósito L, He B, Xu M, Mellacheruvu D, Watkins SC, Modesti M, Miller KM, Nesvizhskii AI, Zhang H, Sung P, O'Sullivan RJ. Kaminski N, et al. Mol Cell. 2022 Nov 3;82(21):4001-4017.e7. doi: 10.1016/j.molcel.2022.09.025. Epub 2022 Oct 19. Mol Cell. 2022. PMID: 36265488 Free PMC article.
New twists to the ALTernative endings at telomeres.
Bhargava R, Lynskey ML, O'Sullivan RJ. Bhargava R, et al. DNA Repair (Amst). 2022 Jul;115:103342. doi: 10.1016/j.dnarep.2022.103342. Epub 2022 May 13. DNA Repair (Amst). 2022. PMID: 35588569 Free PMC article. Review.
Unrestrained poly-ADP-ribosylation provides insights into chromatin regulation and human disease.
Prokhorova E, Agnew T, Wondisford AR, Tellier M, Kaminski N, Beijer D, Holder J, Groslambert J, Suskiewicz MJ, Zhu K, Reber JM, Krassnig SC, Palazzo L, Murphy S, Nielsen ML, Mangerich A, Ahel D, Baets J, O'Sullivan RJ, Ahel I. Prokhorova E, et al. Mol Cell. 2021 Jun 17;81(12):2640-2655.e8. doi: 10.1016/j.molcel.2021.04.028. Epub 2021 May 20. Mol Cell. 2021. PMID: 34019811 Free PMC article.
23 results