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Year Number of Results
2016 2
2017 6
2018 6
2019 4
2020 4
2021 3
2022 2
2023 2
2024 0

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IAP and HDAC inhibitors interact synergistically in myeloma cells through noncanonical NF-κB- and caspase-8-dependent mechanisms.
Zhou L, Zhang Y, Meads MB, Dai Y, Ning Y, Hu X, Li L, Sharma K, Nkwocha J, Parker R, Bui D, McCarter J, Kramer L, Purcell C, Sudalagunta PR, Canevarolo RR, Coelho Siqueira Silva MD, De Avila G, Alugubelli RR, Silva AS, Kmeiciak M, Ferreira-Gonzalez A, Shain KH, Grant S. Zhou L, et al. Blood Adv. 2021 Oct 12;5(19):3776-3788. doi: 10.1182/bloodadvances.2020003597. Blood Adv. 2021. PMID: 34464977 Free PMC article.
Targeting cereblon in AML.
Grant S. Grant S. Blood. 2021 Feb 4;137(5):584-586. doi: 10.1182/blood.2020009827. Blood. 2021. PMID: 33538804 Free PMC article. No abstract available.
Phase 1 study of belinostat (PXD-101) and bortezomib (Velcade, PS-341) in patients with relapsed or refractory acute leukemia and myelodysplastic syndrome.
Holkova B, Shafer D, Yazbeck V, Dave S, Bose P, Tombes MB, Shrader E, Wan W, Bandyopadhyay D, Weir C, Collins EB, Garnett A, Kmieciak M, Roberts JD, Garcia-Manero G, Grant S. Holkova B, et al. Leuk Lymphoma. 2021 May;62(5):1187-1194. doi: 10.1080/10428194.2020.1861270. Epub 2020 Dec 28. Leuk Lymphoma. 2021. PMID: 33356689 Free PMC article. Clinical Trial.
Enhancing venetoclax activity in hematological malignancies.
Satta T, Grant S. Satta T, et al. Expert Opin Investig Drugs. 2020 Jul;29(7):697-708. doi: 10.1080/13543784.2020.1789588. Epub 2020 Jul 16. Expert Opin Investig Drugs. 2020. PMID: 32600066 Free PMC article. Review.
Concomitant targeting of BCL2 with venetoclax and MAPK signaling with cobimetinib in acute myeloid leukemia models.
Han L, Zhang Q, Dail M, Shi C, Cavazos A, Ruvolo VR, Zhao Y, Kim E, Rahmani M, Mak DH, Jin SS, Chen J, Phillips DC, Koller PB, Jacamo R, Burks JK, DiNardo C, Daver N, Jabbour E, Wang J, Kantarjian HM, Andreeff M, Grant S, Leverson JD, Sampath D, Konopleva M. Han L, et al. Haematologica. 2020 Mar;105(3):697-707. doi: 10.3324/haematol.2018.205534. Epub 2019 May 23. Haematologica. 2020. PMID: 31123034 Free PMC article.
23 results