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Year | Number of Results |
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Loss of MGA repression mediated by an atypical polycomb complex promotes tumor progression and invasiveness.
Elife. 2021 Jul 8;10:e64212. doi: 10.7554/eLife.64212.
Elife. 2021.
PMID: 34236315
Free PMC article.
MYCN drives chemoresistance in small cell lung cancer while USP7 inhibition can restore chemosensitivity.
Grunblatt E, Wu N, Zhang H, Liu X, Norton JP, Ohol Y, Leger P, Hiatt JB, Eastwood EC, Thomas R, Ibrahim AH, Jia D, Basom R, Eaton KD, Martins R, Houghton AM, MacPherson D.
Grunblatt E, et al.
Genes Dev. 2020 Sep 1;34(17-18):1210-1226. doi: 10.1101/gad.340133.120. Epub 2020 Aug 20.
Genes Dev. 2020.
PMID: 32820040
Free PMC article.
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MAX Functions as a Tumor Suppressor and Rewires Metabolism in Small Cell Lung Cancer.
Augert A, Mathsyaraja H, Ibrahim AH, Freie B, Geuenich MJ, Cheng PF, Alibeckoff SP, Wu N, Hiatt JB, Basom R, Gazdar A, Sullivan LB, Eisenman RN, MacPherson D.
Augert A, et al.
Cancer Cell. 2020 Jul 13;38(1):97-114.e7. doi: 10.1016/j.ccell.2020.04.016. Epub 2020 May 28.
Cancer Cell. 2020.
PMID: 32470392
Free PMC article.
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Targeting NOTCH activation in small cell lung cancer through LSD1 inhibition.
Augert A, Eastwood E, Ibrahim AH, Wu N, Grunblatt E, Basom R, Liggitt D, Eaton KD, Martins R, Poirier JT, Rudin CM, Milletti F, Cheng WY, Mack F, MacPherson D.
Augert A, et al.
Sci Signal. 2019 Feb 5;12(567):eaau2922. doi: 10.1126/scisignal.aau2922.
Sci Signal. 2019.
PMID: 30723171
Free PMC article.
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Crebbp Loss Drives Small Cell Lung Cancer and Increases Sensitivity to HDAC Inhibition.
Jia D, Augert A, Kim DW, Eastwood E, Wu N, Ibrahim AH, Kim KB, Dunn CT, Pillai SPS, Gazdar AF, Bolouri H, Park KS, MacPherson D.
Jia D, et al.
Cancer Discov. 2018 Nov;8(11):1422-1437. doi: 10.1158/2159-8290.CD-18-0385. Epub 2018 Sep 4.
Cancer Discov. 2018.
PMID: 30181244
Free PMC article.
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Small Cell Lung Cancer Exhibits Frequent Inactivating Mutations in the Histone Methyltransferase KMT2D/MLL2: CALGB 151111 (Alliance).
Augert A, Zhang Q, Bates B, Cui M, Wang X, Wildey G, Dowlati A, MacPherson D.
Augert A, et al.
J Thorac Oncol. 2017 Apr;12(4):704-713. doi: 10.1016/j.jtho.2016.12.011. Epub 2016 Dec 19.
J Thorac Oncol. 2017.
PMID: 28007623
Free PMC article.
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