R01 CA177684/CA/NCI NIH HHS/United States[Grants and Funding] - Search Results

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Subject: R01 CA177684/CA/NCI NIH HHS/United States[Grants - PubMed

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Year	Number of Results
2013	2
2015	1
2016	2
2017	3
2019	1
2021	2
2022	2
2023	10
2024	0

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DGKα/ζ inhibition lowers the TCR affinity threshold and potentiates antitumor immunity.

Kureshi R, Bello E, Kureshi CTS, Walsh MJ, Lippert V, Hoffman MT, Dougan M, Longmire T, Wichroski M, Dougan SK. Kureshi R, et al. Sci Adv. 2023 Nov 24;9(47):eadk1853. doi: 10.1126/sciadv.adk1853. Epub 2023 Nov 24. Sci Adv. 2023. PMID: 38000024 Free PMC article.

TCR ligand potency differentially impacts PD-1 inhibitory effects on diverse signaling pathways.

Chan W, Cao YM, Zhao X, Schrom EC, Jia D, Song J, Sibener LV, Dong S, Fernandes RA, Bradfield CJ, Smelkinson M, Kabat J, Hor JL, Altan-Bonnet G, Garcia KC, Germain RN. Chan W, et al. J Exp Med. 2023 Dec 4;220(12):e20231242. doi: 10.1084/jem.20231242. Epub 2023 Oct 5. J Exp Med. 2023. PMID: 37796477 Free PMC article.

Epitope base editing CD45 in hematopoietic cells enables universal blood cancer immune therapy.

Wellhausen N, O'Connell RP, Lesch S, Engel NW, Rennels AK, Gonzales D, Herbst F, Young RM, Garcia KC, Weiner D, June CH, Gill SI. Wellhausen N, et al. Sci Transl Med. 2023 Sep 20;15(714):eadi1145. doi: 10.1126/scitranslmed.adi1145. Epub 2023 Sep 20. Sci Transl Med. 2023. PMID: 37651540 Free PMC article.

Gastrointestinal mucosal toxicities from immune checkpoint inhibitors: Current understanding and future directions.

Dougan M. Dougan M. Immunol Rev. 2023 Sep;318(1):11-21. doi: 10.1111/imr.13239. Epub 2023 Jul 16. Immunol Rev. 2023. PMID: 37455375 Review.

Evaluation of appendectomy as a potential risk factor for immune checkpoint inhibitor-associated enterocolitis.

Krasnow NA, Chute DF, Falade AS, North CM, Reynolds KL, Dougan ML. Krasnow NA, et al. Immunotherapy. 2023 Aug;15(12):913-920. doi: 10.2217/imt-2022-0245. Epub 2023 Jun 9. Immunotherapy. 2023. PMID: 37292001

Transforming Growth Factor-β Blockade in Pancreatic Cancer Enhances Sensitivity to Combination Chemotherapy.

Qiang L, Hoffman MT, Ali LR, Castillo JI, Kageler L, Temesgen A, Lenehan P, Wang SJ, Bello E, Cardot-Ruffino V, Uribe GA, Yang A, Dougan M, Aguirre AJ, Raghavan S, Pelletier M, Cremasco V, Dougan SK. Qiang L, et al. Gastroenterology. 2023 Oct;165(4):874-890.e10. doi: 10.1053/j.gastro.2023.05.038. Epub 2023 May 30. Gastroenterology. 2023. PMID: 37263309

Immune mechanisms of toxicity from checkpoint inhibitors.

Wang SJ, Dougan SK, Dougan M. Wang SJ, et al. Trends Cancer. 2023 Jul;9(7):543-553. doi: 10.1016/j.trecan.2023.04.002. Epub 2023 Apr 27. Trends Cancer. 2023. PMID: 37117135 Free article. Review.

Receptor Elimination by E3 Ubiquitin Ligase Recruitment (REULR): A Targeted Protein Degradation Toolbox.

Siepe DH, Picton LK, Garcia KC. Siepe DH, et al. ACS Synth Biol. 2023 Apr 21;12(4):1081-1093. doi: 10.1021/acssynbio.2c00587. Epub 2023 Apr 3. ACS Synth Biol. 2023. PMID: 37011906 Free PMC article.

cIAP1/2 Antagonism Induces Antigen-Specific T Cell-Dependent Immunity.

Ventre KS, Roehle K, Bello E, Bhuiyan AM, Biary T, Crowley SJ, Bruck PT, Heckler M, Lenehan PJ, Ali LR, Stump CT, Lippert V, Clancy-Thompson E, Conce Alberto WD, Hoffman MT, Qiang L, Pelletier M, Akin JJ, Dougan M, Dougan SK. Ventre KS, et al. J Immunol. 2023 Apr 1;210(7):991-1003. doi: 10.4049/jimmunol.2200646. J Immunol. 2023. PMID: 36881882 Free PMC article.

PD-1 blockade and CDK4/6 inhibition augment nonoverlapping features of T cell activation in cancer.

Ali LR, Garrido-Castro AC, Lenehan PJ, Bollenrucher N, Stump CT, Dougan M, Goel S, Shapiro GI, Tolaney SM, Dougan SK. Ali LR, et al. J Exp Med. 2023 Apr 3;220(4):e20220729. doi: 10.1084/jem.20220729. Epub 2023 Jan 23. J Exp Med. 2023. PMID: 36688919 Free PMC article.

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