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Circulating and Intratumoral Adrenal Androgens Correlate with Response to Abiraterone in Men with Castration-Resistant Prostate Cancer.
Mostaghel EA, Marck BT, Kolokythas O, Chew F, Yu EY, Schweizer MT, Cheng HH, Kantoff PW, Balk SP, Taplin ME, Sharifi N, Matsumoto AM, Nelson PS, Montgomery RB. Mostaghel EA, et al. Clin Cancer Res. 2021 Nov 1;27(21):6001-6011. doi: 10.1158/1078-0432.CCR-21-1819. Epub 2021 Aug 18. Clin Cancer Res. 2021. PMID: 34407973 Free PMC article. Clinical Trial.
Targeting the perivascular niche sensitizes disseminated tumour cells to chemotherapy.
Carlson P, Dasgupta A, Grzelak CA, Kim J, Barrett A, Coleman IM, Shor RE, Goddard ET, Dai J, Schweitzer EM, Lim AR, Crist SB, Cheresh DA, Nelson PS, Hansen KC, Ghajar CM. Carlson P, et al. Nat Cell Biol. 2019 Feb;21(2):238-250. doi: 10.1038/s41556-018-0267-0. Epub 2019 Jan 21. Nat Cell Biol. 2019. PMID: 30664790 Free PMC article.
A proteolytic modification of AIM promotes its renal excretion.
Yamazaki T, Sugisawa R, Hiramoto E, Takai R, Matsumoto A, Senda Y, Nakashima K, Nelson PS, Lucas JM, Morgan A, Li Z, Yamamura KI, Arai S, Miyazaki T. Yamazaki T, et al. Sci Rep. 2016 Dec 8;6:38762. doi: 10.1038/srep38762. Sci Rep. 2016. PMID: 27929116 Free PMC article.
19 results