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Page 1
Post-translational modification of RAS proteins.
Campbell SL, Philips MR. Campbell SL, et al. Curr Opin Struct Biol. 2021 Dec;71:180-192. doi: 10.1016/j.sbi.2021.06.015. Epub 2021 Aug 6. Curr Opin Struct Biol. 2021. PMID: 34365229 Free PMC article. Review.
Scaffold association factor B (SAFB) is required for expression of prenyltransferases and RAS membrane association.
Zhou M, Kuruvilla L, Shi X, Viviano S, Ahearn IM, Amendola CR, Su W, Badri S, Mahaffey J, Fehrenbacher N, Skok J, Schlessinger J, Turk BE, Calderwood DA, Philips MR. Zhou M, et al. Proc Natl Acad Sci U S A. 2020 Dec 15;117(50):31914-31922. doi: 10.1073/pnas.2005712117. Epub 2020 Nov 30. Proc Natl Acad Sci U S A. 2020. PMID: 33257571 Free PMC article.
KRAS4A directly regulates hexokinase 1.
Amendola CR, Mahaffey JP, Parker SJ, Ahearn IM, Chen WC, Zhou M, Court H, Shi J, Mendoza SL, Morten MJ, Rothenberg E, Gottlieb E, Wadghiri YZ, Possemato R, Hubbard SR, Balmain A, Kimmelman AC, Philips MR. Amendola CR, et al. Nature. 2019 Dec;576(7787):482-486. doi: 10.1038/s41586-019-1832-9. Epub 2019 Dec 11. Nature. 2019. PMID: 31827279 Free PMC article.
The G protein-coupled receptor GPR31 promotes membrane association of KRAS.
Fehrenbacher N, Tojal da Silva I, Ramirez C, Zhou Y, Cho KJ, Kuchay S, Shi J, Thomas S, Pagano M, Hancock JF, Bar-Sagi D, Philips MR. Fehrenbacher N, et al. J Cell Biol. 2017 Aug 7;216(8):2329-2338. doi: 10.1083/jcb.201609096. Epub 2017 Jun 15. J Cell Biol. 2017. PMID: 28619714 Free PMC article.
20 results