R01 CA160436/CA/NCI NIH HHS/United States[Grants and Funding] - Search Results

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Subject: R01 CA160436/CA/NCI NIH HHS/United States[Grants - PubMed

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Year	Number of Results
2012	2
2013	4
2014	4
2015	7
2017	2
2018	3
2019	1
2021	1
2024	0

21 results

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Wnt-β-catenin activation epigenetically reprograms T_reg cells in inflammatory bowel disease and dysplastic progression.

Quandt J, Arnovitz S, Haghi L, Woehlk J, Mohsin A, Okoreeh M, Mathur PS, Emmanuel AO, Osman A, Krishnan M, Morin SB, Pearson AT, Sweis RF, Pekow J, Weber CR, Khazaie K, Gounari F. Quandt J, et al. Nat Immunol. 2021 Apr;22(4):471-484. doi: 10.1038/s41590-021-00889-2. Epub 2021 Mar 4. Nat Immunol. 2021. PMID: 33664518 Free PMC article.

Cell Intrinsic Deregulated ß-Catenin Signaling Promotes Expansion of Bone Marrow Derived Connective Tissue Type Mast Cells, Systemic Inflammation, and Colon Cancer.

Saadalla A, Lima MM, Tsai F, Osman A, Singh MP, Linden DR, Dennis KL, Haeryfar SMM, Gurish MF, Gounari F, Khazaie K. Saadalla A, et al. Front Immunol. 2019 Dec 3;10:2777. doi: 10.3389/fimmu.2019.02777. eCollection 2019. Front Immunol. 2019. PMID: 31849960 Free PMC article.

TCF-1 and HEB cooperate to establish the epigenetic and transcription profiles of CD4⁺CD8⁺ thymocytes.

Emmanuel AO, Arnovitz S, Haghi L, Mathur PS, Mondal S, Quandt J, Okoreeh MK, Maienschein-Cline M, Khazaie K, Dose M, Gounari F. Emmanuel AO, et al. Nat Immunol. 2018 Dec;19(12):1366-1378. doi: 10.1038/s41590-018-0254-4. Epub 2018 Nov 12. Nat Immunol. 2018. PMID: 30420627 Free PMC article.

Mast cells promote small bowel cancer in a tumor stage-specific and cytokine-dependent manner.

Saadalla AM, Osman A, Gurish MF, Dennis KL, Blatner NR, Pezeshki A, McNagny KM, Cheroutre H, Gounari F, Khazaie K. Saadalla AM, et al. Proc Natl Acad Sci U S A. 2018 Feb 13;115(7):1588-1592. doi: 10.1073/pnas.1716804115. Epub 2018 Feb 2. Proc Natl Acad Sci U S A. 2018. PMID: 29429965 Free PMC article.

The STAT3 inhibitor pyrimethamine displays anti-cancer and immune stimulatory effects in murine models of breast cancer.

Khan MW, Saadalla A, Ewida AH, Al-Katranji K, Al-Saoudi G, Giaccone ZT, Gounari F, Zhang M, Frank DA, Khazaie K. Khan MW, et al. Cancer Immunol Immunother. 2018 Jan;67(1):13-23. doi: 10.1007/s00262-017-2057-0. Epub 2017 Sep 5. Cancer Immunol Immunother. 2018. PMID: 28875329 Free PMC article.

Mucosa-associated invariant T cells infiltrate hepatic metastases in patients with colorectal carcinoma but are rendered dysfunctional within and adjacent to tumor microenvironment.

Shaler CR, Tun-Abraham ME, Skaro AI, Khazaie K, Corbett AJ, Mele T, Hernandez-Alejandro R, Haeryfar SMM. Shaler CR, et al. Cancer Immunol Immunother. 2017 Dec;66(12):1563-1575. doi: 10.1007/s00262-017-2050-7. Epub 2017 Aug 10. Cancer Immunol Immunother. 2017. PMID: 28798979 Free PMC article.

The Mutant KRAS Gene Up-regulates BCL-XL Protein via STAT3 to Confer Apoptosis Resistance That Is Reversed by BIM Protein Induction and BCL-XL Antagonism.

Zaanan A, Okamoto K, Kawakami H, Khazaie K, Huang S, Sinicrope FA. Zaanan A, et al. J Biol Chem. 2015 Sep 25;290(39):23838-49. doi: 10.1074/jbc.M115.657833. Epub 2015 Aug 5. J Biol Chem. 2015. PMID: 26245900 Free PMC article.

Preferential expansion of pro-inflammatory Tregs in human non-small cell lung cancer.

Phillips JD, Knab LM, Blatner NR, Haghi L, DeCamp MM, Meyerson SL, Heiferman MJ, Heiferman JR, Gounari F, Bentrem DJ, Khazaie K. Phillips JD, et al. Cancer Immunol Immunother. 2015 Sep;64(9):1185-91. doi: 10.1007/s00262-015-1725-1. Epub 2015 Jun 6. Cancer Immunol Immunother. 2015. PMID: 26047578 Free PMC article.

T-cell Expression of IL10 Is Essential for Tumor Immune Surveillance in the Small Intestine.

Dennis KL, Saadalla A, Blatner NR, Wang S, Venkateswaran V, Gounari F, Cheroutre H, Weaver CT, Roers A, Egilmez NK, Khazaie K. Dennis KL, et al. Cancer Immunol Res. 2015 Jul;3(7):806-14. doi: 10.1158/2326-6066.CIR-14-0169. Epub 2015 Apr 8. Cancer Immunol Res. 2015. PMID: 25855122 Free PMC article.

Zileuton, 5-lipoxygenase inhibitor, acts as a chemopreventive agent in intestinal polyposis, by modulating polyp and systemic inflammation.

Gounaris E, Heiferman MJ, Heiferman JR, Shrivastav M, Vitello D, Blatner NR, Knab LM, Phillips JD, Cheon EC, Grippo PJ, Khazaie K, Munshi HG, Bentrem DJ. Gounaris E, et al. PLoS One. 2015 Mar 6;10(3):e0121402. doi: 10.1371/journal.pone.0121402. eCollection 2015. PLoS One. 2015. PMID: 25747113 Free PMC article.

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