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Nitrostyrene Derivatives Act as RXRα Ligands to Inhibit TNFα Activation of NF-κB.
Zeng Z, Sun Z, Huang M, Zhang W, Liu J, Chen L, Chen F, Zhou Y, Lin J, Huang F, Xu L, Zhuang Z, Guo S, Alitongbieke G, Xie G, Xu Y, Lin B, Cao X, Su Y, Zhang XK, Zhou H. Zeng Z, et al. Cancer Res. 2015 May 15;75(10):2049-60. doi: 10.1158/0008-5472.CAN-14-2435. Epub 2015 Mar 20. Cancer Res. 2015. PMID: 25795708 Free PMC article.
Sulindac-derived RXRα modulators inhibit cancer cell growth by binding to a novel site.
Chen L, Wang ZG, Aleshin AE, Chen F, Chen J, Jiang F, Alitongbieke G, Zeng Z, Ma Y, Huang M, Zhou H, Cadwell G, Zheng JF, Huang PQ, Liddington RC, Zhang XK, Su Y. Chen L, et al. Chem Biol. 2014 May 22;21(5):596-607. doi: 10.1016/j.chembiol.2014.02.017. Epub 2014 Apr 3. Chem Biol. 2014. PMID: 24704507 Free PMC article.
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