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An integrated in vitro and in vivo high-throughput screen identifies treatment leads for ependymoma.
Cancer Cell. 2011 Sep 13;20(3):384-99. doi: 10.1016/j.ccr.2011.08.013.
Cancer Cell. 2011.
PMID: 21907928
Free PMC article.
Subtypes of medulloblastoma have distinct developmental origins.
Gibson P, Tong Y, Robinson G, Thompson MC, Currle DS, Eden C, Kranenburg TA, Hogg T, Poppleton H, Martin J, Finkelstein D, Pounds S, Weiss A, Patay Z, Scoggins M, Ogg R, Pei Y, Yang ZJ, Brun S, Lee Y, Zindy F, Lindsey JC, Taketo MM, Boop FA, Sanford RA, Gajjar A, Clifford SC, Roussel MF, McKinnon PJ, Gutmann DH, Ellison DW, Wechsler-Reya R, Gilbertson RJ.
Gibson P, et al.
Nature. 2010 Dec 23;468(7327):1095-9. doi: 10.1038/nature09587. Epub 2010 Dec 8.
Nature. 2010.
PMID: 21150899
Free PMC article.
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Cross-species genomics matches driver mutations and cell compartments to model ependymoma.
Johnson RA, Wright KD, Poppleton H, Mohankumar KM, Finkelstein D, Pounds SB, Rand V, Leary SE, White E, Eden C, Hogg T, Northcott P, Mack S, Neale G, Wang YD, Coyle B, Atkinson J, DeWire M, Kranenburg TA, Gillespie Y, Allen JC, Merchant T, Boop FA, Sanford RA, Gajjar A, Ellison DW, Taylor MD, Grundy RG, Gilbertson RJ.
Johnson RA, et al.
Nature. 2010 Jul 29;466(7306):632-6. doi: 10.1038/nature09173. Epub 2010 Jul 18.
Nature. 2010.
PMID: 20639864
Free PMC article.
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Prominin 1 marks intestinal stem cells that are susceptible to neoplastic transformation.
Zhu L, Gibson P, Currle DS, Tong Y, Richardson RJ, Bayazitov IT, Poppleton H, Zakharenko S, Ellison DW, Gilbertson RJ.
Zhu L, et al.
Nature. 2009 Jan 29;457(7229):603-7. doi: 10.1038/nature07589. Epub 2008 Dec 17.
Nature. 2009.
PMID: 19092805
Free PMC article.
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