R01 CA064140/CA/NCI NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
1997	1
1998	3
1999	2
2000	2
2001	1
2003	2
2005	2
2007	1
2008	6
2009	1
2010	5
2011	2
2012	2
2013	3
2015	2
2016	2
2017	4
2018	2
2019	5
2020	2
2021	1
2023	1
2024	1

1

Histone deacetylases maintain expression of the pluripotent gene network via recruitment of RNA polymerase II to coding and noncoding loci.

Kelly RDW, Stengel KR, Chandru A, Johnson LC, Hiebert SW, Cowley SM. Kelly RDW, et al. Genome Res. 2024 Feb 7;34(1):34-46. doi: 10.1101/gr.278050.123. Genome Res. 2024. PMID: 38290976 Free PMC article.

2

Histone Deacetylases (HDACs) maintain expression of the pluripotent gene network via recruitment of RNA polymerase II to coding and non-coding loci.

Rdw K, Kr S, A C, Lc J, Sw H, Sm C. Rdw K, et al. bioRxiv [Preprint]. 2023 Apr 6:2023.04.06.535398. doi: 10.1101/2023.04.06.535398. bioRxiv. 2023. PMID: 37066171 Free PMC article. Updated. Preprint.

3

Definition of a small core transcriptional circuit regulated by AML1-ETO.

Stengel KR, Ellis JD, Spielman CL, Bomber ML, Hiebert SW. Stengel KR, et al. Mol Cell. 2021 Feb 4;81(3):530-545.e5. doi: 10.1016/j.molcel.2020.12.005. Epub 2020 Dec 30. Mol Cell. 2021. PMID: 33382982 Free PMC article.

4

Nascent transcript and single-cell RNA-seq analysis defines the mechanism of action of the LSD1 inhibitor INCB059872 in myeloid leukemia.

Johnston G, Ramsey HE, Liu Q, Wang J, Stengel KR, Sampathi S, Acharya P, Arrate M, Stubbs MC, Burn T, Savona MR, Hiebert SW. Johnston G, et al. Gene. 2020 Aug 20;752:144758. doi: 10.1016/j.gene.2020.144758. Epub 2020 May 15. Gene. 2020. PMID: 32422235 Free PMC article.

5

Deletion of intestinal Hdac3 remodels the lipidome of enterocytes and protects mice from diet-induced obesity.

Dávalos-Salas M, Montgomery MK, Reehorst CM, Nightingale R, Ng I, Anderton H, Al-Obaidi S, Lesmana A, Scott CM, Ioannidis P, Kalra H, Keerthikumar S, Tögel L, Rigopoulos A, Gong SJ, Williams DS, Yoganantharaja P, Bell-Anderson K, Mathivanan S, Gibert Y, Hiebert S, Scott AM, Watt MJ, Mariadason JM. Dávalos-Salas M, et al. Nat Commun. 2019 Nov 22;10(1):5291. doi: 10.1038/s41467-019-13180-8. Nat Commun. 2019. PMID: 31757939 Free PMC article.

6

Histone deacetylase 3 controls a transcriptional network required for B cell maturation.

Stengel KR, Bhaskara S, Wang J, Liu Q, Ellis JD, Sampathi S, Hiebert SW. Stengel KR, et al. Nucleic Acids Res. 2019 Nov 18;47(20):10612-10627. doi: 10.1093/nar/gkz816. Nucleic Acids Res. 2019. PMID: 31586401 Free PMC article.

7

Displacement of WDR5 from Chromatin by a WIN Site Inhibitor with Picomolar Affinity.

Aho ER, Wang J, Gogliotti RD, Howard GC, Phan J, Acharya P, Macdonald JD, Cheng K, Lorey SL, Lu B, Wenzel S, Foshage AM, Alvarado J, Wang F, Shaw JG, Zhao B, Weissmiller AM, Thomas LR, Vakoc CR, Hall MD, Hiebert SW, Liu Q, Stauffer SR, Fesik SW, Tansey WP. Aho ER, et al. Cell Rep. 2019 Mar 12;26(11):2916-2928.e13. doi: 10.1016/j.celrep.2019.02.047. Cell Rep. 2019. PMID: 30865883 Free PMC article.

8

The CDK7 inhibitor THZ1 alters RNA polymerase dynamics at the 5' and 3' ends of genes.

Sampathi S, Acharya P, Zhao Y, Wang J, Stengel KR, Liu Q, Savona MR, Hiebert SW. Sampathi S, et al. Nucleic Acids Res. 2019 May 7;47(8):3921-3936. doi: 10.1093/nar/gkz127. Nucleic Acids Res. 2019. PMID: 30805632 Free PMC article.

9

BET inhibitors reduce cell size and induce reversible cell cycle arrest in AML.

Zhang S, Zhao Y, Heaster TM, Fischer MA, Stengel KR, Zhou X, Ramsey H, Zhou MM, Savona MR, Skala MC, Hiebert SW. Zhang S, et al. J Cell Biochem. 2019 May;120(5):7309-7322. doi: 10.1002/jcb.28005. Epub 2018 Nov 11. J Cell Biochem. 2019. PMID: 30417424 Free PMC article.

10

The assembly competence domain is essential for inv(16)-associated acute myeloid leukemia.

Kim HG, LeGrand J, Swindle CS, Nick HJ, Oster RA, Chen D, Purohit-Ghelani S, Cotta CV, Ko R, Gartland L, Reddy V, Hiebert SW, Friedman AD, Klug CA. Kim HG, et al. Leukemia. 2017 Oct;31(10):2267-2271. doi: 10.1038/leu.2017.236. Epub 2017 Jul 28. Leukemia. 2017. PMID: 28751774 Free PMC article. No abstract available.

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