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IgM antibodies derived from memory B cells are potent cross-variant neutralizers of SARS-CoV-2.
Hale M, Netland J, Chen Y, Thouvenel CD, Smith KN, Rich LM, Vanderwall ER, Miranda MC, Eggenberger J, Hao L, Watson MJ, Mundorff CC, Rodda LB, King NP, Guttman M, Gale M, Abraham J, Debley JS, Pepper M, Rawlings DJ. Hale M, et al. J Exp Med. 2022 Sep 5;219(9):e20220849. doi: 10.1084/jem.20220849. Epub 2022 Aug 8. J Exp Med. 2022. PMID: 35938988 Free PMC article.
Cullin-independent recognition of HHARI substrates by a dynamic RBR catalytic domain.
Reiter KH, Zelter A, Janowska MK, Riffle M, Shulman N, MacLean BX, Tamura K, Chambers MC, MacCoss MJ, Davis TN, Guttman M, Brzovic PS, Klevit RE. Reiter KH, et al. Structure. 2022 Sep 1;30(9):1269-1284.e6. doi: 10.1016/j.str.2022.05.017. Epub 2022 Jun 17. Structure. 2022. PMID: 35716664 Free PMC article.