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Discovery, Crystallographic Studies, and Mechanistic Investigations of Novel Phenylalanine Derivatives Bearing a Quinazolin-4-one Scaffold as Potent HIV Capsid Modulators.
Xu S, Sun L, Barnett M, Zhang X, Ding D, Gattu A, Shi D, Taka JRH, Shen W, Jiang X, Cocklin S, De Clercq E, Pannecouque C, Goldstone DC, Liu X, Dick A, Zhan P. Xu S, et al. J Med Chem. 2023 Dec 14;66(23):16303-16329. doi: 10.1021/acs.jmedchem.3c01647. Epub 2023 Dec 6. J Med Chem. 2023. PMID: 38054267 Free PMC article.
Design, synthesis, and mechanistic investigations of phenylalanine derivatives containing a benzothiazole moiety as HIV-1 capsid inhibitors with improved metabolic stability.
Xu S, Sun L, Dick A, Zalloum WA, Huang T, Meuser ME, Zhang X, Tao Y, Cherukupalli S, Ding D, Ding X, Gao S, Jiang X, Kang D, De Clercq E, Pannecouque C, Cocklin S, Liu X, Zhan P. Xu S, et al. Eur J Med Chem. 2022 Jan 5;227:113903. doi: 10.1016/j.ejmech.2021.113903. Epub 2021 Oct 9. Eur J Med Chem. 2022. PMID: 34653770 Free PMC article.
21 results