R01 AI150455/AI/NIAID NIH HHS/United States[Grants and Funding] - Search Results

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Subject: R01 AI150455/AI/NIAID NIH HHS/United States[Grant - PubMed

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Year	Number of Results
2019	1
2020	1
2021	3
2022	3
2023	1
2024	2

11 results

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Release of P-TEFb from the Super Elongation Complex promotes HIV-1 latency reversal.

Cisneros WJ, Walter M, Soliman SHA, Simons LM, Cornish D, Halle AW, Kim EY, Wolinsky SM, Shilatifard A, Hultquist JF. Cisneros WJ, et al. bioRxiv [Preprint]. 2024 Mar 1:2024.03.01.582881. doi: 10.1101/2024.03.01.582881. bioRxiv. 2024. PMID: 38464055 Free PMC article. Preprint.

Host ZCCHC3 blocks HIV-1 infection and production through a dual mechanism.

Yi B, Tanaka YL, Cornish D, Kosako H, Butlertanaka EP, Sengupta P, Lippincott-Schwartz J, Hultquist JF, Saito A, Yoshimura SH. Yi B, et al. iScience. 2024 Feb 5;27(3):109107. doi: 10.1016/j.isci.2024.109107. eCollection 2024 Mar 15. iScience. 2024. PMID: 38384847 Free PMC article.

Enhancing HIV-1 latency reversal through regulating the elongating RNA Pol II pause-release by a small-molecule disruptor of PAF1C.

Soliman SHA, Cisneros WJ, Iwanaszko M, Aoi Y, Ganesan S, Walter M, Zeidner JM, Mishra RK, Kim EY, Wolinsky SM, Hultquist JF, Shilatifard A. Soliman SHA, et al. Sci Adv. 2023 Mar 10;9(10):eadf2468. doi: 10.1126/sciadv.adf2468. Epub 2023 Mar 8. Sci Adv. 2023. PMID: 36888719 Free PMC article.

Rab11-FIP1C Is Dispensable for HIV-1 Replication in Primary CD4⁺ T Cells, but Its Role Is Cell Type Dependent in Immortalized Human T-Cell Lines.

Fernandez-de Céspedes MV, Hoffman HK, Carter H, Simons LM, Naing L, Ablan SD, Scheiblin DA, Hultquist JF, van Engelenburg SB, Freed EO. Fernandez-de Céspedes MV, et al. J Virol. 2022 Dec 14;96(23):e0087622. doi: 10.1128/jvi.00876-22. Epub 2022 Nov 10. J Virol. 2022. PMID: 36354340 Free PMC article.

Application of CRISPR-Cas9 Gene Editing for HIV Host Factor Discovery and Validation.

Cisneros WJ, Cornish D, Hultquist JF. Cisneros WJ, et al. Pathogens. 2022 Aug 9;11(8):891. doi: 10.3390/pathogens11080891. Pathogens. 2022. PMID: 36015010 Free PMC article. Review.

Recognition of HIV-1 capsid by PQBP1 licenses an innate immune sensing of nascent HIV-1 DNA.

Yoh SM, Mamede JI, Lau D, Ahn N, Sánchez-Aparicio MT, Temple J, Tuckwell A, Fuchs NV, Cianci GC, Riva L, Curry H, Yin X, Gambut S, Simons LM, Hultquist JF, König R, Xiong Y, García-Sastre A, Böcking T, Hope TJ, Chanda SK. Yoh SM, et al. Mol Cell. 2022 Aug 4;82(15):2871-2884.e6. doi: 10.1016/j.molcel.2022.06.010. Epub 2022 Jul 8. Mol Cell. 2022. PMID: 35809572 Free PMC article.

Structural and functional characterization explains loss of dNTPase activity of the cancer-specific R366C/H mutant SAMHD1 proteins.

Bowen NE, Temple J, Shepard C, Oo A, Arizaga F, Kapoor-Vazirani P, Persaud M, Yu CH, Kim DH, Schinazi RF, Ivanov DN, Diaz-Griffero F, Yu DS, Xiong Y, Kim B. Bowen NE, et al. J Biol Chem. 2021 Oct;297(4):101170. doi: 10.1016/j.jbc.2021.101170. Epub 2021 Sep 4. J Biol Chem. 2021. PMID: 34492268 Free PMC article.

SUMOylation of SAMHD1 at Lysine 595 is required for HIV-1 restriction in non-cycling cells.

Martinat C, Cormier A, Tobaly-Tapiero J, Palmic N, Casartelli N, Mahboubi B, Coggins SA, Buchrieser J, Persaud M, Diaz-Griffero F, Espert L, Bossis G, Lesage P, Schwartz O, Kim B, Margottin-Goguet F, Saïb A, Zamborlini A. Martinat C, et al. Nat Commun. 2021 Jul 28;12(1):4582. doi: 10.1038/s41467-021-24802-5. Nat Commun. 2021. PMID: 34321470 Free PMC article.

Nucleic acid binding by SAMHD1 contributes to the antiretroviral activity and is enhanced by the GpsN modification.

Yu CH, Bhattacharya A, Persaud M, Taylor AB, Wang Z, Bulnes-Ramos A, Xu J, Selyutina A, Martinez-Lopez A, Cano K, Demeler B, Kim B, Hardies SC, Diaz-Griffero F, Ivanov DN. Yu CH, et al. Nat Commun. 2021 Feb 2;12(1):731. doi: 10.1038/s41467-021-21023-8. Nat Commun. 2021. PMID: 33531504 Free PMC article.

Cyclophilin A Prevents HIV-1 Restriction in Lymphocytes by Blocking Human TRIM5α Binding to the Viral Core.

Selyutina A, Persaud M, Simons LM, Bulnes-Ramos A, Buffone C, Martinez-Lopez A, Scoca V, Di Nunzio F, Hiatt J, Marson A, Krogan NJ, Hultquist JF, Diaz-Griffero F. Selyutina A, et al. Cell Rep. 2020 Mar 17;30(11):3766-3777.e6. doi: 10.1016/j.celrep.2020.02.100. Cell Rep. 2020. PMID: 32187548 Free PMC article.

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