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Immunoengineering can overcome the glycocalyx armour of cancer cells.
Park S, Colville MJ, Paek JH, Shurer CR, Singh A, Secor EJ, Sailer CJ, Huang LT, Kuo JC, Goudge MC, Su J, Kim M, DeLisa MP, Neelamegham S, Lammerding J, Zipfel WR, Fischbach C, Reesink HL, Paszek MJ. Park S, et al. Nat Mater. 2024 Mar;23(3):429-438. doi: 10.1038/s41563-024-01808-0. Epub 2024 Feb 15. Nat Mater. 2024. PMID: 38361041
ST3GAL1 and βII-spectrin pathways control CAR T cell migration to target tumors.
Hong Y, Walling BL, Kim HR, Serratelli WS, Lozada JR, Sailer CJ, Amitrano AM, Lim K, Mongre RK, Kim KD, Capece T, Lomakina EB, Reilly NS, Vo K, Gerber SA, Fan TC, Yu AL, Oakes PW, Waugh RE, Jun CD, Reagan PM, Kim M. Hong Y, et al. Nat Immunol. 2023 Jun;24(6):1007-1019. doi: 10.1038/s41590-023-01498-x. Epub 2023 Apr 17. Nat Immunol. 2023. PMID: 37069398 Free PMC article.
Optical Control of CD8+ T Cell Metabolism and Effector Functions.
Amitrano AM, Berry BJ, Lim K, Kim KD, Waugh RE, Wojtovich AP, Kim M. Amitrano AM, et al. Front Immunol. 2021 Jun 3;12:666231. doi: 10.3389/fimmu.2021.666231. eCollection 2021. Front Immunol. 2021. PMID: 34149701 Free PMC article.