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Page 1
Slow progression of pediatric HIV associates with early CD8+ T cell PD-1 expression and a stem-like phenotype.
Vieira V, Lim N, Singh A, Leitman E, Dsouza R, Adland E, Muenchhoff M, Roider J, Marin Lopez M, Carabelli J, Giandhari J, Groll A, Jooste P, Prado JG, Thobakgale C, Dong K, Kiepiela P, Prendergast AJ, Tudor-Williams G, Frater J, Walker BD, Ndung'u T, Ramsuran V, Leslie A, Kløverpris HN, Goulder P. Vieira V, et al. JCI Insight. 2023 Feb 8;8(3):e156049. doi: 10.1172/jci.insight.156049. JCI Insight. 2023. PMID: 36602861 Free PMC article.
HIV specific CD8+ TRM-like cells in tonsils express exhaustive signatures in the absence of natural HIV control.
Fardoos R, Nyquist SK, Asowata OE, Kazer SW, Singh A, Ngoepe A, Giandhari J, Mthabela N, Ramjit D, Singh S, Karim F, Buus S, Anderson F, Porterfield JZ, Sibiya AL, Bipath R, Moodley K, Kuhn W, Berger B, Nguyen S, de Oliveira T, Ndung'u T, Goulder P, Shalek AK, Leslie A, Kløverpris HN. Fardoos R, et al. Front Immunol. 2022 Oct 18;13:912038. doi: 10.3389/fimmu.2022.912038. eCollection 2022. Front Immunol. 2022. PMID: 36330531 Free PMC article.
Determinants of B-Cell Compartment Hyperactivation in European Adolescents Living With Perinatally Acquired HIV-1 After Over 10 Years of Suppressive Therapy.
Ruggiero A, Pascucci GR, Cotugno N, Domínguez-Rodríguez S, Rinaldi S, Tagarro A, Rojo P, Foster C, Bamford A, De Rossi A, Nastouli E, Klein N, Morrocchi E, Fatou B, Smolen KK, Ozonoff A, Di Pastena M, Luzuriaga K, Steen H, Giaquinto C, Goulder P, Rossi P, Levy O, Pahwa S, Palma P; EPIICAL Consortium. Ruggiero A, et al. Front Immunol. 2022 Mar 31;13:860418. doi: 10.3389/fimmu.2022.860418. eCollection 2022. Front Immunol. 2022. PMID: 35432380 Free PMC article.
A simple, robust flow cytometry-based whole blood assay for investigating sex differential interferon alpha production by plasmacytoid dendritic cells.
Sampson O, Lim N, White J, Vieira V, Kløverpris H, Adland E, Conlon C, Skelly D, Jones L, Stafford L, Jamsen A, Barnes E, Dunachie S, Frater J, Klenerman P, Altfeld M, Goulder P. Sampson O, et al. J Immunol Methods. 2022 May;504:113263. doi: 10.1016/j.jim.2022.113263. Epub 2022 Mar 24. J Immunol Methods. 2022. PMID: 35341760 Free PMC article.
An HLA-I signature favouring KIR-educated Natural Killer cells mediates immune control of HIV in children and contrasts with the HLA-B-restricted CD8+ T-cell-mediated immune control in adults.
Vieira VA, Adland E, Malone DFG, Martin MP, Groll A, Ansari MA, Garcia-Guerrero MC, Puertas MC, Muenchhoff M, Guash CF, Brander C, Martinez-Picado J, Bamford A, Tudor-Williams G, Ndung'u T, Walker BD, Ramsuran V, Frater J, Jooste P, Peppa D, Carrington M, Goulder PJR. Vieira VA, et al. PLoS Pathog. 2021 Nov 18;17(11):e1010090. doi: 10.1371/journal.ppat.1010090. eCollection 2021 Nov. PLoS Pathog. 2021. PMID: 34793581 Free PMC article.
Robust HIV-specific CD4+ and CD8+ T-cell responses distinguish elite control in adolescents living with HIV from viremic nonprogressors.
Vieira VA, Millar J, Adland E, Muenchhoff M, Roider J, Guash CF, Peluso D, Thomé B, Garcia-Guerrero MC, Puertas MC, Bamford A, Brander C, Carrington M, Martinez-Picado J, Frater J, Tudor-Williams G, Goulder P. Vieira VA, et al. AIDS. 2022 Jan 1;36(1):95-105. doi: 10.1097/QAD.0000000000003078. AIDS. 2022. PMID: 34581306 Free PMC article.
41 results