R01 AI129868/AI/NIAID NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2017	2
2018	1
2019	7
2020	8
2021	5
2022	1
2023	2
2024	0

1

Effect of mRNA-LNP components of two globally-marketed COVID-19 vaccines on efficacy and stability.

Zhang L, More KR, Ojha A, Jackson CB, Quinlan BD, Li H, He W, Farzan M, Pardi N, Choe H. Zhang L, et al. NPJ Vaccines. 2023 Oct 11;8(1):156. doi: 10.1038/s41541-023-00751-6. NPJ Vaccines. 2023. PMID: 37821446 Free PMC article.

2

Cytoplasmic Tail Truncation Stabilizes S1-S2 Association and Enhances S Protein Incorporation into SARS-CoV-2 Pseudovirions.

Zhang L, Hom N, Ojha A, Lovendahl KN, Mou H, Lee KK, Choe H. Zhang L, et al. J Virol. 2023 Mar 30;97(3):e0165022. doi: 10.1128/jvi.01650-22. Epub 2023 Feb 15. J Virol. 2023. PMID: 36790205 Free PMC article.

3

Mechanisms of SARS-CoV-2 entry into cells.

Jackson CB, Farzan M, Chen B, Choe H. Jackson CB, et al. Nat Rev Mol Cell Biol. 2022 Jan;23(1):3-20. doi: 10.1038/s41580-021-00418-x. Epub 2021 Oct 5. Nat Rev Mol Cell Biol. 2022. PMID: 34611326 Free PMC article. Review.

4

An Engineered Receptor-Binding Domain Improves the Immunogenicity of Multivalent SARS-CoV-2 Vaccines.

Guo Y, He W, Mou H, Zhang L, Chang J, Peng S, Ojha A, Tavora R, Parcells MS, Luo G, Li W, Zhong G, Choe H, Farzan M, Quinlan BD. Guo Y, et al. mBio. 2021 May 11;12(3):e00930-21. doi: 10.1128/mBio.00930-21. mBio. 2021. PMID: 33975938 Free PMC article.

5

Mutations derived from horseshoe bat ACE2 orthologs enhance ACE2-Fc neutralization of SARS-CoV-2.

Mou H, Quinlan BD, Peng H, Liu G, Guo Y, Peng S, Zhang L, Davis-Gardner ME, Gardner MR, Crynen G, DeVaux LB, Voo ZX, Bailey CC, Alpert MD, Rader C, Gack MU, Choe H, Farzan M. Mou H, et al. PLoS Pathog. 2021 Apr 9;17(4):e1009501. doi: 10.1371/journal.ppat.1009501. eCollection 2021 Apr. PLoS Pathog. 2021. PMID: 33836016 Free PMC article.

6

Hydroxychloroquine-mediated inhibition of SARS-CoV-2 entry is attenuated by TMPRSS2.

Ou T, Mou H, Zhang L, Ojha A, Choe H, Farzan M. Ou T, et al. PLoS Pathog. 2021 Jan 19;17(1):e1009212. doi: 10.1371/journal.ppat.1009212. eCollection 2021 Jan. PLoS Pathog. 2021. PMID: 33465165 Free PMC article.

7

SARS-CoV-2 spike-protein D614G mutation increases virion spike density and infectivity.

Zhang L, Jackson CB, Mou H, Ojha A, Peng H, Quinlan BD, Rangarajan ES, Pan A, Vanderheiden A, Suthar MS, Li W, Izard T, Rader C, Farzan M, Choe H. Zhang L, et al. Nat Commun. 2020 Nov 26;11(1):6013. doi: 10.1038/s41467-020-19808-4. Nat Commun. 2020. PMID: 33243994 Free PMC article.

8

An engineered receptor-binding domain improves the immunogenicity of multivalent SARS-CoV-2 vaccines.

Quinlan BD, He W, Mou H, Zhang L, Guo Y, Chang J, Peng S, Ojha A, Tavora R, Parcells MS, Luo G, Li W, Zhong G, Choe H, Farzan M. Quinlan BD, et al. bioRxiv [Preprint]. 2020 Nov 18:2020.11.18.388934. doi: 10.1101/2020.11.18.388934. bioRxiv. 2020. PMID: 33236008 Free PMC article. Updated. Preprint.

9

Functional importance of the D614G mutation in the SARS-CoV-2 spike protein.

Jackson CB, Zhang L, Farzan M, Choe H. Jackson CB, et al. Biochem Biophys Res Commun. 2021 Jan 29;538:108-115. doi: 10.1016/j.bbrc.2020.11.026. Epub 2020 Nov 13. Biochem Biophys Res Commun. 2021. PMID: 33220921 Free PMC article. Review.

10

A Single Immunization with Nucleoside-Modified mRNA Vaccines Elicits Strong Cellular and Humoral Immune Responses against SARS-CoV-2 in Mice.

Laczkó D, Hogan MJ, Toulmin SA, Hicks P, Lederer K, Gaudette BT, Castaño D, Amanat F, Muramatsu H, Oguin TH 3rd, Ojha A, Zhang L, Mu Z, Parks R, Manzoni TB, Roper B, Strohmeier S, Tombácz I, Arwood L, Nachbagauer R, Karikó K, Greenhouse J, Pessaint L, Porto M, Putman-Taylor T, Strasbaugh A, Campbell TA, Lin PJC, Tam YK, Sempowski GD, Farzan M, Choe H, Saunders KO, Haynes BF, Andersen H, Eisenlohr LC, Weissman D, Krammer F, Bates P, Allman D, Locci M, Pardi N. Laczkó D, et al. Immunity. 2020 Oct 13;53(4):724-732.e7. doi: 10.1016/j.immuni.2020.07.019. Epub 2020 Jul 30. Immunity. 2020. PMID: 32783919 Free PMC article.

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