R01 AI128358/AI/NIAID NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2017	2
2018	2
2019	2
2020	3
2021	3
2022	2
2023	1
2024	1

1

Endothelial cell expression of a STING gain-of-function mutation initiates pulmonary lymphocytic infiltration.

Gao KM, Chiang K, Jiang Z, Korkmaz FT, Janardhan HP, Trivedi CM, Quinton LJ, Gingras S, Fitzgerald KA, Marshak-Rothstein A. Gao KM, et al. Cell Rep. 2024 Apr 23;43(4):114114. doi: 10.1016/j.celrep.2024.114114. Epub 2024 Apr 15. Cell Rep. 2024. PMID: 38625791 Free article.

2

STING-dependent interferon signatures restrict osteoclast differentiation and bone loss in mice.

MacLauchlan S, Kushwaha P, Tai A, Chen S, Manning C, Swarnkar G, Abu-Amer Y, Fitzgerald KA, Sharma S, Gravallese EM. MacLauchlan S, et al. Proc Natl Acad Sci U S A. 2023 Apr 11;120(15):e2210409120. doi: 10.1073/pnas.2210409120. Epub 2023 Apr 6. Proc Natl Acad Sci U S A. 2023. PMID: 37023130 Free PMC article.

3

Radioresistant cells initiate lymphocyte-dependent lung inflammation and IFNγ-dependent mortality in STING gain-of-function mice.

Gao KM, Motwani M, Tedder T, Marshak-Rothstein A, Fitzgerald KA. Gao KM, et al. Proc Natl Acad Sci U S A. 2022 Jun 21;119(25):e2202327119. doi: 10.1073/pnas.2202327119. Epub 2022 Jun 13. Proc Natl Acad Sci U S A. 2022. PMID: 35696583 Free PMC article.

4

Intracellular Sensing of DNA in Autoinflammation and Autoimmunity.

MacLauchlan S, Fitzgerald KA, Gravallese EM. MacLauchlan S, et al. Arthritis Rheumatol. 2022 Oct;74(10):1615-1624. doi: 10.1002/art.42256. Epub 2022 Sep 6. Arthritis Rheumatol. 2022. PMID: 35656967 Free PMC article. Review.

5

Dysbiosis exacerbates colitis by promoting ubiquitination and accumulation of the innate immune adaptor STING in myeloid cells.

Shmuel-Galia L, Humphries F, Lei X, Ceglia S, Wilson R, Jiang Z, Ketelut-Carneiro N, Foley SE, Pechhold S, Houghton J, Muneeruddin K, Shaffer SA, McCormick BA, Reboldi A, Ward D, Marshak-Rothstein A, Fitzgerald KA. Shmuel-Galia L, et al. Immunity. 2021 Jun 8;54(6):1137-1153.e8. doi: 10.1016/j.immuni.2021.05.008. Epub 2021 May 28. Immunity. 2021. PMID: 34051146 Free PMC article.

6

cGAS-STING Pathway Does Not Promote Autoimmunity in Murine Models of SLE.

Motwani M, McGowan J, Antonovitch J, Gao KM, Jiang Z, Sharma S, Baltus GA, Nickerson KM, Marshak-Rothstein A, Fitzgerald KA. Motwani M, et al. Front Immunol. 2021 Mar 29;12:605930. doi: 10.3389/fimmu.2021.605930. eCollection 2021. Front Immunol. 2021. PMID: 33854495 Free PMC article.

7

Overcoming innate immune barriers that impede AAV gene therapy vectors.

Muhuri M, Maeda Y, Ma H, Ram S, Fitzgerald KA, Tai PW, Gao G. Muhuri M, et al. J Clin Invest. 2021 Jan 4;131(1):e143780. doi: 10.1172/JCI143780. J Clin Invest. 2021. PMID: 33393506 Free PMC article. Review.

8

Interplay of Cyclic GMP-AMP Synthase/Stimulator of IFN Genes and Toll-Like Receptor Nucleic Acid Sensing Pathways in Autoinflammation and Abnormal Bone Formation due to DNaseII-Deficiency.

Marshak-Rothstein A, Manning CA, Baum R, Pawaria S, Gravallese EM. Marshak-Rothstein A, et al. Viral Immunol. 2020 Apr;33(3):246-249. doi: 10.1089/vim.2019.0191. Viral Immunol. 2020. PMID: 32286184 Free PMC article.

9

Toll-like Receptors and the Control of Immunity.

Fitzgerald KA, Kagan JC. Fitzgerald KA, et al. Cell. 2020 Mar 19;180(6):1044-1066. doi: 10.1016/j.cell.2020.02.041. Epub 2020 Mar 11. Cell. 2020. PMID: 32164908 Free PMC article. Review.

10

Role of Interferon-γ-Producing Th1 Cells in a Murine Model of Type I Interferon-Independent Autoinflammation Resulting From DNase II Deficiency.

Pawaria S, Nündel K, Gao KM, Moses S, Busto P, Holt K, Sharma RB, Brehm MA, Gravallese EM, Socolovsky M, Christ A, Marshak-Rothstein A. Pawaria S, et al. Arthritis Rheumatol. 2020 Feb;72(2):359-370. doi: 10.1002/art.41090. Epub 2019 Dec 29. Arthritis Rheumatol. 2020. PMID: 31464028 Free PMC article.

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