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A terpene nucleoside from M. tuberculosis induces lysosomal lipid storage in foamy macrophages.
Bedard M, van der Niet S, Bernard EM, Babunovic G, Cheng TY, Aylan B, Grootemaat AE, Raman S, Botella L, Ishikawa E, O'Sullivan MP, O'Leary S, Mayfield JA, Buter J, Minnaard AJ, Fortune SM, Murphy LO, Ory DS, Keane J, Yamasaki S, Gutierrez MG, van der Wel N, Moody DB. Bedard M, et al. J Clin Invest. 2023 Mar 15;133(6):e161944. doi: 10.1172/JCI161944. J Clin Invest. 2023. PMID: 36757797 Free PMC article.
A natural polymorphism of Mycobacterium tuberculosis in the esxH gene disrupts immunodomination by the TB10.4-specific CD8 T cell response.
Sutiwisesak R, Hicks ND, Boyce S, Murphy KC, Papavinasasundaram K, Carpenter SM, Boucau J, Joshi N, Le Gall S, Fortune SM, Sassetti CM, Behar SM. Sutiwisesak R, et al. PLoS Pathog. 2020 Oct 19;16(10):e1009000. doi: 10.1371/journal.ppat.1009000. eCollection 2020 Oct. PLoS Pathog. 2020. PMID: 33075106 Free PMC article.
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