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2013 4
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TLR4 sensing of IsdB of Staphylococcus aureus induces a proinflammatory cytokine response via the NLRP3-caspase-1 inflammasome cascade.
Gonzalez JJI, Hossain MF, Neef J, Zwack EE, Tsai C-M, Raafat D, Fechtner K, Herzog L, Kohler TP, Schlüter R, Reder A, Holtfreter S, Liu GY, Hammerschmidt S, Völker U, Torres VJ, van Dijl JM, Lillig CH, Bröker BM, Darisipudi MN. Gonzalez JJI, et al. mBio. 2024 Jan 16;15(1):e0022523. doi: 10.1128/mbio.00225-23. Epub 2023 Dec 19. mBio. 2024. PMID: 38112465 Free PMC article.
MRSA lineage USA300 isolated from bloodstream infections exhibit altered virulence regulation.
Dyzenhaus S, Sullivan MJ, Alburquerque B, Boff D, van de Guchte A, Chung M, Fulmer Y, Copin R, Ilmain JK, O'Keefe A, Altman DR, Stubbe FX, Podkowik M, Dupper AC, Shopsin B, van Bakel H, Torres VJ. Dyzenhaus S, et al. Cell Host Microbe. 2023 Feb 8;31(2):228-242.e8. doi: 10.1016/j.chom.2022.12.003. Epub 2023 Jan 20. Cell Host Microbe. 2023. PMID: 36681080 Free PMC article.
The influenza-injured lung microenvironment promotes MRSA virulence, contributing to severe secondary bacterial pneumonia.
Langouët-Astrié C, Oshima K, McMurtry SA, Yang Y, Kwiecinski JM, LaRivière WB, Kavanaugh JS, Zakharevich I, Hansen KC, Shi D, Zhang F, Boguslawski KM, Perelman SS, Su G, Torres VJ, Liu J, Horswill AR, Schmidt EP. Langouët-Astrié C, et al. Cell Rep. 2022 Nov 29;41(9):111721. doi: 10.1016/j.celrep.2022.111721. Cell Rep. 2022. PMID: 36450248 Free PMC article.
ACE2-containing defensosomes serve as decoys to inhibit SARS-CoV-2 infection.
Ching KL, de Vries M, Gago J, Dancel-Manning K, Sall J, Rice WJ, Barnett C, Khodadadi-Jamayran A, Tsirigos A, Liang FX, Thorpe LE, Shopsin B, Segal LN, Dittmann M, Torres VJ, Cadwell K. Ching KL, et al. PLoS Biol. 2022 Sep 13;20(9):e3001754. doi: 10.1371/journal.pbio.3001754. eCollection 2022 Sep. PLoS Biol. 2022. PMID: 36099266 Free PMC article.
65 results