R01 AI084817/AI/NIAID NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2010	5
2011	6
2012	7
2013	11
2014	8
2015	12
2016	10
2017	7
2018	2
2024	0

1

HIV-1 vaccine design through minimizing envelope metastability.

He L, Kumar S, Allen JD, Huang D, Lin X, Mann CJ, Saye-Francisco KL, Copps J, Sarkar A, Blizard GS, Ozorowski G, Sok D, Crispin M, Ward AB, Nemazee D, Burton DR, Wilson IA, Zhu J. He L, et al. Sci Adv. 2018 Nov 21;4(11):eaau6769. doi: 10.1126/sciadv.aau6769. eCollection 2018 Nov. Sci Adv. 2018. PMID: 30474059 Free PMC article.

2

Structure of a cleavage-independent HIV Env recapitulates the glycoprotein architecture of the native cleaved trimer.

Sarkar A, Bale S, Behrens AJ, Kumar S, Sharma SK, de Val N, Pallesen J, Irimia A, Diwanji DC, Stanfield RL, Ward AB, Crispin M, Wyatt RT, Wilson IA. Sarkar A, et al. Nat Commun. 2018 May 16;9(1):1956. doi: 10.1038/s41467-018-04272-y. Nat Commun. 2018. PMID: 29769533 Free PMC article.

3

Bacterially derived synthetic mimetics of mammalian oligomannose prime antibody responses that neutralize HIV infectivity.

Pantophlet R, Trattnig N, Murrell S, Lu N, Chau D, Rempel C, Wilson IA, Kosma P. Pantophlet R, et al. Nat Commun. 2017 Nov 17;8(1):1601. doi: 10.1038/s41467-017-01640-y. Nat Commun. 2017. PMID: 29150603 Free PMC article.

4

Hidden Lineage Complexity of Glycan-Dependent HIV-1 Broadly Neutralizing Antibodies Uncovered by Digital Panning and Native-Like gp140 Trimer.

He L, Lin X, de Val N, Saye-Francisco KL, Mann CJ, Augst R, Morris CD, Azadnia P, Zhou B, Sok D, Ozorowski G, Ward AB, Burton DR, Zhu J. He L, et al. Front Immunol. 2017 Aug 24;8:1025. doi: 10.3389/fimmu.2017.01025. eCollection 2017. Front Immunol. 2017. PMID: 28883821 Free PMC article.

5

Selection of nanobodies with broad neutralizing potential against primary HIV-1 strains using soluble subtype C gp140 envelope trimers.

Koch K, Kalusche S, Torres JL, Stanfield RL, Danquah W, Khazanehdari K, von Briesen H, Geertsma ER, Wilson IA, Wernery U, Koch-Nolte F, Ward AB, Dietrich U. Koch K, et al. Sci Rep. 2017 Aug 21;7(1):8390. doi: 10.1038/s41598-017-08273-7. Sci Rep. 2017. PMID: 28827559 Free PMC article.

6

Open and closed structures reveal allostery and pliability in the HIV-1 envelope spike.

Ozorowski G, Pallesen J, de Val N, Lyumkis D, Cottrell CA, Torres JL, Copps J, Stanfield RL, Cupo A, Pugach P, Moore JP, Wilson IA, Ward AB. Ozorowski G, et al. Nature. 2017 Jul 20;547(7663):360-363. doi: 10.1038/nature23010. Epub 2017 Jul 12. Nature. 2017. PMID: 28700571 Free PMC article.

7

Glycine Substitution at Helix-to-Coil Transitions Facilitates the Structural Determination of a Stabilized Subtype C HIV Envelope Glycoprotein.

Guenaga J, Garces F, de Val N, Stanfield RL, Dubrovskaya V, Higgins B, Carrette B, Ward AB, Wilson IA, Wyatt RT. Guenaga J, et al. Immunity. 2017 May 16;46(5):792-803.e3. doi: 10.1016/j.immuni.2017.04.014. Immunity. 2017. PMID: 28514686 Free PMC article.

8

T cells control the generation of nanomolar-affinity anti-glycan antibodies.

Polonskaya Z, Deng S, Sarkar A, Kain L, Comellas-Aragones M, McKay CS, Kaczanowska K, Holt M, McBride R, Palomo V, Self KM, Taylor S, Irimia A, Mehta SR, Dan JM, Brigger M, Crotty S, Schoenberger SP, Paulson JC, Wilson IA, Savage PB, Finn MG, Teyton L. Polonskaya Z, et al. J Clin Invest. 2017 Apr 3;127(4):1491-1504. doi: 10.1172/JCI91192. Epub 2017 Mar 13. J Clin Invest. 2017. PMID: 28287405 Free PMC article.

9

The HIV-1 envelope glycoprotein structure: nailing down a moving target.

Ward AB, Wilson IA. Ward AB, et al. Immunol Rev. 2017 Jan;275(1):21-32. doi: 10.1111/imr.12507. Immunol Rev. 2017. PMID: 28133813 Free PMC article. Review.

10

HIV Vaccine Design to Target Germline Precursors of Glycan-Dependent Broadly Neutralizing Antibodies.

Steichen JM, Kulp DW, Tokatlian T, Escolano A, Dosenovic P, Stanfield RL, McCoy LE, Ozorowski G, Hu X, Kalyuzhniy O, Briney B, Schiffner T, Garces F, Freund NT, Gitlin AD, Menis S, Georgeson E, Kubitz M, Adachi Y, Jones M, Mutafyan AA, Yun DS, Mayer CT, Ward AB, Burton DR, Wilson IA, Irvine DJ, Nussenzweig MC, Schief WR. Steichen JM, et al. Immunity. 2016 Sep 20;45(3):483-496. doi: 10.1016/j.immuni.2016.08.016. Epub 2016 Sep 8. Immunity. 2016. PMID: 27617678 Free PMC article.

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