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Sulfur(VI) Fluoride Exchange (SuFEx)-Enabled High-Throughput Medicinal Chemistry.
Kitamura S, Zheng Q, Woehl JL, Solania A, Chen E, Dillon N, Hull MV, Kotaniguchi M, Cappiello JR, Kitamura S, Nizet V, Sharpless KB, Wolan DW. Kitamura S, et al. J Am Chem Soc. 2020 Jun 24;142(25):10899-10904. doi: 10.1021/jacs.9b13652. Epub 2020 Jun 10. J Am Chem Soc. 2020. PMID: 32479075 Free PMC article.
Recurrent group A Streptococcus tonsillitis is an immunosusceptibility disease involving antibody deficiency and aberrant TFH cells.
Dan JM, Havenar-Daughton C, Kendric K, Al-Kolla R, Kaushik K, Rosales SL, Anderson EL, LaRock CN, Vijayanand P, Seumois G, Layfield D, Cutress RI, Ottensmeier CH, Lindestam Arlehamn CS, Sette A, Nizet V, Bothwell M, Brigger M, Crotty S. Dan JM, et al. Sci Transl Med. 2019 Feb 6;11(478):eaau3776. doi: 10.1126/scitranslmed.aau3776. Sci Transl Med. 2019. PMID: 30728285 Free PMC article.
Streptococcal Lancefield polysaccharides are critical cell wall determinants for human Group IIA secreted phospholipase A2 to exert its bactericidal effects.
van Hensbergen VP, Movert E, de Maat V, Lüchtenborg C, Le Breton Y, Lambeau G, Payré C, Henningham A, Nizet V, van Strijp JAG, Brügger B, Carlsson F, McIver KS, van Sorge NM. van Hensbergen VP, et al. PLoS Pathog. 2018 Oct 15;14(10):e1007348. doi: 10.1371/journal.ppat.1007348. eCollection 2018 Oct. PLoS Pathog. 2018. PMID: 30321240 Free PMC article.
95 results