R01 AI048540/AI/NIAID NIH HHS/United States[Grants and Funding] - Search Results

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Subject: R01 AI048540/AI/NIAID NIH HHS/United States[Grant - PubMed

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Year	Number of Results
2008	2
2009	3
2011	1
2012	4
2014	1
2015	1
2016	2
2017	1
2018	2
2021	2
2022	1
2024	0

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Tuning T cell receptor sensitivity through catch bond engineering.

Zhao X, Kolawole EM, Chan W, Feng Y, Yang X, Gee MH, Jude KM, Sibener LV, Fordyce PM, Germain RN, Evavold BD, Garcia KC. Zhao X, et al. Science. 2022 Apr 8;376(6589):eabl5282. doi: 10.1126/science.abl5282. Epub 2022 Apr 8. Science. 2022. PMID: 35389803 Free PMC article.

The tissue protective functions of interleukin-22 can be decoupled from pro-inflammatory actions through structure-based design.

Saxton RA, Henneberg LT, Calafiore M, Su L, Jude KM, Hanash AM, Garcia KC. Saxton RA, et al. Immunity. 2021 Apr 13;54(4):660-672.e9. doi: 10.1016/j.immuni.2021.03.008. Immunity. 2021. PMID: 33852830 Free PMC article.

Structural basis for IL-12 and IL-23 receptor sharing reveals a gateway for shaping actions on T versus NK cells.

Glassman CR, Mathiharan YK, Jude KM, Su L, Panova O, Lupardus PJ, Spangler JB, Ely LK, Thomas C, Skiniotis G, Garcia KC. Glassman CR, et al. Cell. 2021 Feb 18;184(4):983-999.e24. doi: 10.1016/j.cell.2021.01.018. Cell. 2021. PMID: 33606986 Free PMC article.

Isolation of a Structural Mechanism for Uncoupling T Cell Receptor Signaling from Peptide-MHC Binding.

Sibener LV, Fernandes RA, Kolawole EM, Carbone CB, Liu F, McAffee D, Birnbaum ME, Yang X, Su LF, Yu W, Dong S, Gee MH, Jude KM, Davis MM, Groves JT, Goddard WA 3rd, Heath JR, Evavold BD, Vale RD, Garcia KC. Sibener LV, et al. Cell. 2018 Jul 26;174(3):672-687.e27. doi: 10.1016/j.cell.2018.06.017. Cell. 2018. PMID: 30053426 Free PMC article.

Antigen Identification for Orphan T Cell Receptors Expressed on Tumor-Infiltrating Lymphocytes.

Gee MH, Han A, Lofgren SM, Beausang JF, Mendoza JL, Birnbaum ME, Bethune MT, Fischer S, Yang X, Gomez-Eerland R, Bingham DB, Sibener LV, Fernandes RA, Velasco A, Baltimore D, Schumacher TN, Khatri P, Quake SR, Davis MM, Garcia KC. Gee MH, et al. Cell. 2018 Jan 25;172(3):549-563.e16. doi: 10.1016/j.cell.2017.11.043. Epub 2017 Dec 21. Cell. 2018. PMID: 29275860 Free PMC article.

Genetic variation in MHC proteins is associated with T cell receptor expression biases.

Sharon E, Sibener LV, Battle A, Fraser HB, Garcia KC, Pritchard JK. Sharon E, et al. Nat Genet. 2016 Sep;48(9):995-1002. doi: 10.1038/ng.3625. Epub 2016 Aug 1. Nat Genet. 2016. PMID: 27479906 Free PMC article.

Structural interplay between germline interactions and adaptive recognition determines the bandwidth of TCR-peptide-MHC cross-reactivity.

Adams JJ, Narayanan S, Birnbaum ME, Sidhu SS, Blevins SJ, Gee MH, Sibener LV, Baker BM, Kranz DM, Garcia KC. Adams JJ, et al. Nat Immunol. 2016 Jan;17(1):87-94. doi: 10.1038/ni.3310. Epub 2015 Nov 2. Nat Immunol. 2016. PMID: 26523866 Free PMC article.

Deconstructing the peptide-MHC specificity of T cell recognition.

Birnbaum ME, Mendoza JL, Sethi DK, Dong S, Glanville J, Dobbins J, Ozkan E, Davis MM, Wucherpfennig KW, Garcia KC. Birnbaum ME, et al. Cell. 2014 May 22;157(5):1073-87. doi: 10.1016/j.cell.2014.03.047. Cell. 2014. PMID: 24855945 Free PMC article.

Diversity-oriented approaches for interrogating T-cell receptor repertoire, ligand recognition, and function.

Birnbaum ME, Dong S, Garcia KC. Birnbaum ME, et al. Immunol Rev. 2012 Nov;250(1):82-101. doi: 10.1111/imr.12006. Immunol Rev. 2012. PMID: 23046124 Free PMC article. Review.

Insights into immune structure, recognition, and signaling.

Garcia KC. Garcia KC. Immunol Rev. 2012 Nov;250(1):5-9. doi: 10.1111/imr.12007. Immunol Rev. 2012. PMID: 23046119 Free PMC article. No abstract available.

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