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Native-state proteomics of Parvalbumin interneurons identifies unique molecular signatures and vulnerabilities to early Alzheimer's pathology.
Kumar P, Goettemoeller AM, Espinosa-Garcia C, Tobin BR, Tfaily A, Nelson RS, Natu A, Dammer EB, Santiago JV, Malepati S, Cheng L, Xiao H, Duong DD, Seyfried NT, Wood LB, Rowan MJM, Rangaraju S. Kumar P, et al. Nat Commun. 2024 Apr 1;15(1):2823. doi: 10.1038/s41467-024-47028-7. Nat Commun. 2024. PMID: 38561349 Free PMC article.
Native-state proteomics of Parvalbumin interneurons identifies novel molecular signatures and metabolic vulnerabilities to early Alzheimer's disease pathology.
Kumar P, Goettemoeller AM, Espinosa-Garcia C, Tobin BR, Tfaily A, Nelson RS, Natu A, Dammer EB, Santiago JV, Malepati S, Cheng L, Xiao H, Duong D, Seyfried NT, Wood LB, Rowan MJ, Rangaraju S. Kumar P, et al. bioRxiv [Preprint]. 2023 May 17:2023.05.17.541038. doi: 10.1101/2023.05.17.541038. bioRxiv. 2023. PMID: 37292756 Free PMC article. Updated. Preprint.
APOE expression and secretion are modulated by mitochondrial dysfunction.
Wynne ME, Ogunbona O, Lane AR, Gokhale A, Zlatic SA, Xu C, Wen Z, Duong DM, Rayaprolu S, Ivanova A, Ortlund EA, Dammer EB, Seyfried NT, Roberts BR, Crocker A, Shanbhag V, Petris M, Senoo N, Kandasamy S, Claypool SM, Barrientos A, Wingo A, Wingo TS, Rangaraju S, Levey AI, Werner E, Faundez V. Wynne ME, et al. Elife. 2023 May 12;12:e85779. doi: 10.7554/eLife.85779. Elife. 2023. PMID: 37171075 Free PMC article.
13 results