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2021 6
2022 4
2023 2
2024 2

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The efficacy of chemotherapy is limited by intratumoral senescent cells expressing PD-L2.
Chaib S, López-Domínguez JA, Lalinde-Gutiérrez M, Prats N, Marin I, Boix O, García-Garijo A, Meyer K, Muñoz MI, Aguilera M, Mateo L, Stephan-Otto Attolini C, Llanos S, Pérez-Ramos S, Escorihuela M, Al-Shahrour F, Cash TP, Tchkonia T, Kirkland JL, Abad M, Gros A, Arribas J, Serrano M. Chaib S, et al. Nat Cancer. 2024 Mar;5(3):448-462. doi: 10.1038/s43018-023-00712-x. Epub 2024 Jan 24. Nat Cancer. 2024. PMID: 38267628 Free PMC article.
Targeting cellular senescence in metabolic disease.
Palmer AK, Tchkonia T, Kirkland JL. Palmer AK, et al. Mol Metab. 2022 Dec;66:101601. doi: 10.1016/j.molmet.2022.101601. Epub 2022 Sep 16. Mol Metab. 2022. PMID: 36116755 Free PMC article. Review.
Chronic HIV Infection and Aging: Application of a Geroscience-Guided Approach.
Masters MC, Landay AL, Robbins PD, Tchkonia T, Kirkland JL, Kuchel GA, Niedernhofer LJ, Palella FJ. Masters MC, et al. J Acquir Immune Defic Syndr. 2022 Feb 1;89(Suppl 1):S34-S46. doi: 10.1097/QAI.0000000000002858. J Acquir Immune Defic Syndr. 2022. PMID: 35015744 Free PMC article.
Strategies for Targeting Senescent Cells in Human Disease.
Gasek NS, Kuchel GA, Kirkland JL, Xu M. Gasek NS, et al. Nat Aging. 2021 Oct;1(10):870-879. doi: 10.1038/s43587-021-00121-8. Epub 2021 Oct 7. Nat Aging. 2021. PMID: 34841261 Free PMC article. Review.
Role of senescence in the chronic health consequences of COVID-19.
Wissler Gerdes EO, Vanichkachorn G, Verdoorn BP, Hanson GJ, Joshi AY, Murad MH, Rizza SA, Hurt RT, Tchkonia T, Kirkland JL. Wissler Gerdes EO, et al. Transl Res. 2022 Mar;241:96-108. doi: 10.1016/j.trsl.2021.10.003. Epub 2021 Oct 22. Transl Res. 2022. PMID: 34695606 Free PMC article. Review.
Fisetin for COVID-19 in skilled nursing facilities: Senolytic trials in the COVID era.
Verdoorn BP, Evans TK, Hanson GJ, Zhu Y, Langhi Prata LGP, Pignolo RJ, Atkinson EJ, Wissler-Gerdes EO, Kuchel GA, Mannick JB, Kritchevsky SB, Khosla S, Rizza SA, Walston JD, Musi N, Lipsitz LA, Kiel DP, Yung R, LeBrasseur NK, Singh RJ, McCarthy T, Puskarich MA, Niedernhofer LJ, Robbins PD, Sorenson M, Tchkonia T, Kirkland JL. Verdoorn BP, et al. J Am Geriatr Soc. 2021 Nov;69(11):3023-3033. doi: 10.1111/jgs.17416. Epub 2021 Aug 20. J Am Geriatr Soc. 2021. PMID: 34375437 Free PMC article.
12 results