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Oxylipin biosynthesis reinforces cellular senescence and allows detection of senolysis.
Wiley CD, Sharma R, Davis SS, Lopez-Dominguez JA, Mitchell KP, Wiley S, Alimirah F, Kim DE, Payne T, Rosko A, Aimontche E, Deshpande SM, Neri F, Kuehnemann C, Demaria M, Ramanathan A, Campisi J. Wiley CD, et al. Cell Metab. 2021 Jun 1;33(6):1124-1136.e5. doi: 10.1016/j.cmet.2021.03.008. Epub 2021 Apr 2. Cell Metab. 2021. PMID: 33811820 Free PMC article.
JNK modifies neuronal metabolism to promote proteostasis and longevity.
Wang L, Davis SS, Borch Jensen M, Rodriguez-Fernandez IA, Apaydin C, Juhasz G, Gibson BW, Schilling B, Ramanathan A, Ghaemmaghami S, Jasper H. Wang L, et al. Aging Cell. 2019 Jun;18(3):e12849. doi: 10.1111/acel.12849. Epub 2019 Feb 27. Aging Cell. 2019. PMID: 30810280 Free PMC article.