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2018 2
2019 5
2020 4
2021 3
2022 3
2024 0

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Absence of microglia promotes diverse pathologies and early lethality in Alzheimer's disease mice.
Kiani Shabestari S, Morabito S, Danhash EP, McQuade A, Sanchez JR, Miyoshi E, Chadarevian JP, Claes C, Coburn MA, Hasselmann J, Hidalgo J, Tran KN, Martini AC, Chang Rothermich W, Pascual J, Head E, Hume DA, Pridans C, Davtyan H, Swarup V, Blurton-Jones M. Kiani Shabestari S, et al. Cell Rep. 2022 Jun 14;39(11):110961. doi: 10.1016/j.celrep.2022.110961. Cell Rep. 2022. PMID: 35705056 Free PMC article.
The P522R protective variant of PLCG2 promotes the expression of antigen presentation genes by human microglia in an Alzheimer's disease mouse model.
Claes C, England WE, Danhash EP, Kiani Shabestari S, Jairaman A, Chadarevian JP, Hasselmann J, Tsai AP, Coburn MA, Sanchez J, Lim TE, Hidalgo JLS, Tu C, Cahalan MD, Lamb BT, Landreth GE, Spitale RC, Blurton-Jones M, Davtyan H. Claes C, et al. Alzheimers Dement. 2022 Oct;18(10):1765-1778. doi: 10.1002/alz.12577. Epub 2022 Feb 9. Alzheimers Dement. 2022. PMID: 35142046 Free PMC article.
C9orf72 deficiency promotes microglial-mediated synaptic loss in aging and amyloid accumulation.
Lall D, Lorenzini I, Mota TA, Bell S, Mahan TE, Ulrich JD, Davtyan H, Rexach JE, Muhammad AKMG, Shelest O, Landeros J, Vazquez M, Kim J, Ghaffari L, O'Rourke JG, Geschwind DH, Blurton-Jones M, Holtzman DM, Sattler R, Baloh RH. Lall D, et al. Neuron. 2021 Jul 21;109(14):2275-2291.e8. doi: 10.1016/j.neuron.2021.05.020. Epub 2021 Jun 15. Neuron. 2021. PMID: 34133945 Free PMC article.
Gene expression and functional deficits underlie TREM2-knockout microglia responses in human models of Alzheimer's disease.
McQuade A, Kang YJ, Hasselmann J, Jairaman A, Sotelo A, Coburn M, Shabestari SK, Chadarevian JP, Fote G, Tu CH, Danhash E, Silva J, Martinez E, Cotman C, Prieto GA, Thompson LM, Steffan JS, Smith I, Davtyan H, Cahalan M, Cho H, Blurton-Jones M. McQuade A, et al. Nat Commun. 2020 Oct 23;11(1):5370. doi: 10.1038/s41467-020-19227-5. Nat Commun. 2020. PMID: 33097708 Free PMC article.
17 results