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Acute systemic inflammation exacerbates neuroinflammation in Alzheimer's disease: IL-1β drives amplified responses in primed astrocytes and neuronal network dysfunction.
Lopez-Rodriguez AB, Hennessy E, Murray CL, Nazmi A, Delaney HJ, Healy D, Fagan SG, Rooney M, Stewart E, Lewis A, de Barra N, Scarry P, Riggs-Miller L, Boche D, Cunningham MO, Cunningham C. Lopez-Rodriguez AB, et al. Alzheimers Dement. 2021 Oct;17(10):1735-1755. doi: 10.1002/alz.12341. Epub 2021 Jun 3. Alzheimers Dement. 2021. PMID: 34080771 Free PMC article.
Double stranded RNA drives anti-viral innate immune responses, sickness behavior and cognitive dysfunction dependent on dsRNA length, IFNAR1 expression and age.
McGarry N, Murray CL, Garvey S, Wilkinson A, Tortorelli L, Ryan L, Hayden L, Healy D, Griffin EW, Hennessy E, Arumugam M, Skelly DT, Mitchell KJ, Cunningham C. McGarry N, et al. Brain Behav Immun. 2021 Jul;95:413-428. doi: 10.1016/j.bbi.2021.04.016. Epub 2021 Apr 21. Brain Behav Immun. 2021. PMID: 33892139 Free PMC article.
Delirium.
Wilson JE, Mart MF, Cunningham C, Shehabi Y, Girard TD, MacLullich AMJ, Slooter AJC, Ely EW. Wilson JE, et al. Nat Rev Dis Primers. 2020 Nov 12;6(1):90. doi: 10.1038/s41572-020-00223-4. Nat Rev Dis Primers. 2020. PMID: 33184265 Free PMC article. Review.
Losing Sleep Over Delirium.
Arora RC, Cunningham C. Arora RC, et al. Crit Care Med. 2018 Jun;46(6):1036-1038. doi: 10.1097/CCM.0000000000003141. Crit Care Med. 2018. PMID: 29762414 Free PMC article. No abstract available.