R01 AG015709/AG/NIA NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2000	1
2001	1
2002	1
2005	3
2006	3
2007	2
2008	3
2009	1
2010	1
2011	3
2012	2
2013	4
2014	1
2015	1
2016	3
2017	3
2024	0

1

Iron-induced oligomerization of human FXN81-210 and bacterial CyaY frataxin and the effect of iron chelators.

Ahlgren EC, Fekry M, Wiemann M, Söderberg CA, Bernfur K, Gakh O, Rasmussen M, Højrup P, Emanuelsson C, Isaya G, Al-Karadaghi S. Ahlgren EC, et al. PLoS One. 2017 Dec 4;12(12):e0188937. doi: 10.1371/journal.pone.0188937. eCollection 2017. PLoS One. 2017. PMID: 29200434 Free PMC article.

2

SAXS and stability studies of iron-induced oligomers of bacterial frataxin CyaY.

Fekry M, Alshokry W, Grela P, Tchórzewski M, Ahlgren EC, Söderberg CA, Gakh O, Isaya G, Al-Karadaghi S. Fekry M, et al. PLoS One. 2017 Sep 20;12(9):e0184961. doi: 10.1371/journal.pone.0184961. eCollection 2017. PLoS One. 2017. PMID: 28931050 Free PMC article.

3

Zinc and the iron donor frataxin regulate oligomerization of the scaffold protein to form new Fe-S cluster assembly centers.

Galeano BK, Ranatunga W, Gakh O, Smith DY, Thompson JR, Isaya G. Galeano BK, et al. Metallomics. 2017 Jun 21;9(6):773-801. doi: 10.1039/c7mt00089h. Metallomics. 2017. PMID: 28548666 Free PMC article.

4

Architecture of the Human Mitochondrial Iron-Sulfur Cluster Assembly Machinery.

Gakh O, Ranatunga W, Smith DY 4th, Ahlgren EC, Al-Karadaghi S, Thompson JR, Isaya G. Gakh O, et al. J Biol Chem. 2016 Sep 30;291(40):21296-21321. doi: 10.1074/jbc.M116.738542. Epub 2016 Aug 12. J Biol Chem. 2016. PMID: 27519411 Free PMC article.

5

The Structure of the Complex between Yeast Frataxin and Ferrochelatase: CHARACTERIZATION AND PRE-STEADY STATE REACTION OF FERROUS IRON DELIVERY AND HEME SYNTHESIS.

Söderberg C, Gillam ME, Ahlgren EC, Hunter GA, Gakh O, Isaya G, Ferreira GC, Al-Karadaghi S. Söderberg C, et al. J Biol Chem. 2016 May 27;291(22):11887-98. doi: 10.1074/jbc.M115.701128. Epub 2016 Mar 29. J Biol Chem. 2016. PMID: 27026703 Free PMC article.

6

Architecture of the Yeast Mitochondrial Iron-Sulfur Cluster Assembly Machinery: THE SUB-COMPLEX FORMED BY THE IRON DONOR, Yfh1 PROTEIN, AND THE SCAFFOLD, Isu1 PROTEIN.

Ranatunga W, Gakh O, Galeano BK, Smith DY 4th, Söderberg CA, Al-Karadaghi S, Thompson JR, Isaya G. Ranatunga W, et al. J Biol Chem. 2016 May 6;291(19):10378-98. doi: 10.1074/jbc.M115.712414. Epub 2016 Mar 3. J Biol Chem. 2016. PMID: 26941001 Free PMC article.

7

PMPCA mutations cause abnormal mitochondrial protein processing in patients with non-progressive cerebellar ataxia.

Jobling RK, Assoum M, Gakh O, Blaser S, Raiman JA, Mignot C, Roze E, Dürr A, Brice A, Lévy N, Prasad C, Paton T, Paterson AD, Roslin NM, Marshall CR, Desvignes JP, Roëckel-Trevisiol N, Scherer SW, Rouleau GA, Mégarbané A, Isaya G, Delague V, Yoon G. Jobling RK, et al. Brain. 2015 Jun;138(Pt 6):1505-17. doi: 10.1093/brain/awv057. Epub 2015 Mar 25. Brain. 2015. PMID: 25808372 Free PMC article.

8

Mitochondrial iron-sulfur cluster dysfunction in neurodegenerative disease.

Isaya G. Isaya G. Front Pharmacol. 2014 Mar 3;5:29. doi: 10.3389/fphar.2014.00029. eCollection 2014. Front Pharmacol. 2014. PMID: 24624085 Free PMC article. Review.

9

High-throughput immunoassay for the biochemical diagnosis of Friedreich ataxia in dried blood spots and whole blood.

Oglesbee D, Kroll C, Gakh O, Deutsch EC, Lynch DR, Gavrilova R, Tortorelli S, Raymond K, Gavrilov D, Rinaldo P, Matern D, Isaya G. Oglesbee D, et al. Clin Chem. 2013 Oct;59(10):1461-9. doi: 10.1373/clinchem.2013.207472. Epub 2013 Jul 9. Clin Chem. 2013. PMID: 23838345 Free PMC article.

10

The molecular basis of iron-induced oligomerization of frataxin and the role of the ferroxidation reaction in oligomerization.

Söderberg CAG, Rajan S, Shkumatov AV, Gakh O, Schaefer S, Ahlgren EC, Svergun DI, Isaya G, Al-Karadaghi S. Söderberg CAG, et al. J Biol Chem. 2013 Mar 22;288(12):8156-8167. doi: 10.1074/jbc.M112.442285. Epub 2013 Jan 23. J Biol Chem. 2013. PMID: 23344952 Free PMC article.

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