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Mild membrane depolarization in neurons induces immediate early gene transcription and acutely subdues responses to a successive stimulus.
Rienecker KDA, Poston RG, Segales JS, Finholm IW, Sono MH, Munteanu SJ, Ghaninejad-Esfahani M, Rejepova A, Tejeda-Garibay S, Wickman K, Marron Fernandez de Velasco E, Thayer SA, Saha RN. Rienecker KDA, et al. J Biol Chem. 2022 Sep;298(9):102278. doi: 10.1016/j.jbc.2022.102278. Epub 2022 Jul 19. J Biol Chem. 2022. PMID: 35863435 Free PMC article.
Neuronal G protein-gated K+ channels.
Luo H, Marron Fernandez de Velasco E, Wickman K. Luo H, et al. Am J Physiol Cell Physiol. 2022 Aug 1;323(2):C439-C460. doi: 10.1152/ajpcell.00102.2022. Epub 2022 Jun 15. Am J Physiol Cell Physiol. 2022. PMID: 35704701 Free PMC article. Review.
Suppression of pyramidal neuron G protein-gated inwardly rectifying K+ channel signaling impairs prelimbic cortical function and underlies stress-induced deficits in cognitive flexibility in male, but not female, mice.
Anderson EM, Loke S, Wrucke B, Engelhardt A, Demis S, O'Reilly K, Hess E, Wickman K, Hearing MC. Anderson EM, et al. Neuropsychopharmacology. 2021 Nov;46(12):2158-2169. doi: 10.1038/s41386-021-01063-w. Epub 2021 Jun 23. Neuropsychopharmacology. 2021. PMID: 34158613 Free PMC article.
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