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Aerobic exercise reverses aging-induced depth-dependent decline in cerebral microcirculation.
Shin P, Pian Q, Ishikawa H, Hamanaka G, Mandeville ET, Shuzhen G, Buyin F, Alfadhel M, Allu SR, Şencan-Eğilmez I, Li B, Ran C, Vinogradov SA, Ayata C, Lo EH, Arai K, Devor A, Sakadžić S. Shin P, et al. bioRxiv [Preprint]. 2023 Feb 13:2023.02.12.528244. doi: 10.1101/2023.02.12.528244. bioRxiv. 2023. PMID: 36824939 Free PMC article. Updated. Preprint.
Measurements of cerebral microvascular blood flow, oxygenation, and morphology in a mouse model of whole-brain irradiation-induced cognitive impairment by two-photon microscopy and optical coherence tomography: evidence for microvascular injury in the cerebral white matter.
Li B, Yabluchanskiy A, Tarantini S, Allu SR, Şencan-Eğilmez I, Leng J, Alfadhel MAH, Porter JE, Fu B, Ran C, Erdener SE, Boas DA, Vinogradov SA, Sonntag WE, Csiszar A, Ungvari Z, Sakadžić S. Li B, et al. Geroscience. 2023 Jun;45(3):1491-1510. doi: 10.1007/s11357-023-00735-3. Epub 2023 Feb 16. Geroscience. 2023. PMID: 36792820 Free PMC article.
Baseline oxygen consumption decreases with cortical depth.
Mächler P, Fomin-Thunemann N, Thunemann M, Sætra MJ, Desjardins M, Kılıç K, Amra LN, Martin EA, Chen IA, Şencan-Eğilmez I, Li B, Saisan P, Jiang JX, Cheng Q, Weldy KL, Boas DA, Buxton RB, Einevoll GT, Dale AM, Sakadžić S, Devor A. Mächler P, et al. PLoS Biol. 2022 Oct 27;20(10):e3001440. doi: 10.1371/journal.pbio.3001440. eCollection 2022 Oct. PLoS Biol. 2022. PMID: 36301995 Free PMC article.
Optical measurement of microvascular oxygenation and blood flow responses in awake mouse cortex during functional activation.
Şencan İ, Esipova T, Kılıç K, Li B, Desjardins M, Yaseen MA, Wang H, Porter JE, Kura S, Fu B, Secomb TW, Boas DA, Vinogradov SA, Devor A, Sakadžić S. Şencan İ, et al. J Cereb Blood Flow Metab. 2022 Mar;42(3):510-525. doi: 10.1177/0271678X20928011. Epub 2020 Jun 9. J Cereb Blood Flow Metab. 2022. PMID: 32515672 Free PMC article.