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The cochlea is built to last a lifetime.
Savas JN. Savas JN. Hear Res. 2023 Sep 1;436:108821. doi: 10.1016/j.heares.2023.108821. Epub 2023 Jun 1. Hear Res. 2023. PMID: 37295280 Free PMC article. Review.
Cochlear ribbon synapse maturation requires Nlgn1 and Nlgn3.
Ramirez MA, Ninoyu Y, Miller C, Andrade LR, Edassery S, Bomba-Warczak E, Ortega B, Manor U, Rutherford MA, Friedman RA, Savas JN. Ramirez MA, et al. iScience. 2022 Jul 20;25(8):104803. doi: 10.1016/j.isci.2022.104803. eCollection 2022 Aug 19. iScience. 2022. PMID: 35992071 Free PMC article.
CATACOMB: An endogenous inducible gene that antagonizes H3K27 methylation activity of Polycomb repressive complex 2 via an H3K27M-like mechanism.
Piunti A, Smith ER, Morgan MAJ, Ugarenko M, Khaltyan N, Helmin KA, Ryan CA, Murray DC, Rickels RA, Yilmaz BD, Rendleman EJ, Savas JN, Singer BD, Bulun SE, Shilatifard A. Piunti A, et al. Sci Adv. 2019 Jul 3;5(7):eaax2887. doi: 10.1126/sciadv.aax2887. eCollection 2019 Jul. Sci Adv. 2019. PMID: 31281901 Free PMC article.
Resetting the epigenetic balance of Polycomb and COMPASS function at enhancers for cancer therapy.
Wang L, Zhao Z, Ozark PA, Fantini D, Marshall SA, Rendleman EJ, Cozzolino KA, Louis N, He X, Morgan MA, Takahashi YH, Collings CK, Smith ER, Ntziachristos P, Savas JN, Zou L, Hashizume R, Meeks JJ, Shilatifard A. Wang L, et al. Nat Med. 2018 Jun;24(6):758-769. doi: 10.1038/s41591-018-0034-6. Epub 2018 May 21. Nat Med. 2018. PMID: 29785026 Free PMC article.
24 results