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Table representation of search results timeline featuring number of search results per year.
Year | Number of Results |
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2017 | 1 |
2018 | 1 |
2020 | 2 |
2024 | 0 |
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An acidic residue buried in the dimer interface of isocitrate dehydrogenase 1 (IDH1) helps regulate catalysis and pH sensitivity.
Biochem J. 2020 Aug 28;477(16):2999-3018. doi: 10.1042/BCJ20200311.
Biochem J. 2020.
PMID: 32729927
Free PMC article.
Water Networks and Correlated Motions in Mutant Isocitrate Dehydrogenase 1 (IDH1) Are Critical for Allosteric Inhibitor Binding and Activity.
Chambers JM, Miller W, Quichocho G, Upadhye V, Matteo DA, Bobkov AA, Sohl CD, Schiffer JM.
Chambers JM, et al.
Biochemistry. 2020 Feb 4;59(4):479-490. doi: 10.1021/acs.biochem.9b01023. Epub 2020 Jan 13.
Biochemistry. 2020.
PMID: 31869219
Free PMC article.
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Inhibitor potency varies widely among tumor-relevant human isocitrate dehydrogenase 1 mutants.
Avellaneda Matteo D, Wells GA, Luna LA, Grunseth AJ, Zagnitko O, Scott DA, Hoang A, Luthra A, Swairjo MA, Schiffer JM, Sohl CD.
Avellaneda Matteo D, et al.
Biochem J. 2018 Oct 22;475(20):3221-3238. doi: 10.1042/BCJ20180424.
Biochem J. 2018.
PMID: 30249606
Free PMC article.
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Molecular mechanisms of isocitrate dehydrogenase 1 (IDH1) mutations identified in tumors: The role of size and hydrophobicity at residue 132 on catalytic efficiency.
Avellaneda Matteo D, Grunseth AJ, Gonzalez ER, Anselmo SL, Kennedy MA, Moman P, Scott DA, Hoang A, Sohl CD.
Avellaneda Matteo D, et al.
J Biol Chem. 2017 May 12;292(19):7971-7983. doi: 10.1074/jbc.M117.776179. Epub 2017 Mar 22.
J Biol Chem. 2017.
PMID: 28330869
Free PMC article.
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